Results 21 to 30 of about 36,633 (189)
Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence
Emerging Infectious Diseases, 2018 We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre +7 more
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Vaccines, 2022 Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim +11 more
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Epidemiology and Infection, 1969 SUMMARYIn practically all acute fulminating smallpox infections—haemorrhagic type I cases—there is severe viraemia with 104 or more infective particles of virus per ml. of blood. In most of these patients soluble antigen can be demonstrated in serum by precipitation in agar gel tests, or by the complement-fixation technique. In late haemorrhagic cases (
A W, Downie +4 more
openaire +2 more sources
Eczema Herpeticum and Clinical Criteria for Investigating Smallpox
Emerging Infectious Diseases, 2009 Eczema herpeticum can clinically resemble smallpox. On the basis of the algorithm for rapid evaluation of patients with an acute generalized vesiculopustular rash illness, our patient met criteria for high risk for smallpox.
David A. Boyd +2 more
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Micro/nanorobots for detecting and eliminating biological and chemical warfare agents
BMEMat, EarlyView.Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li +4 more
wiley +1 more source
Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus.
PLoS Pathogens, 2021 Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a bioterrorist threat agent. Recent U.S. Food and Drug Administration approval of the first smallpox
Christina L Hutson +13 more
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Exploration, EarlyView.This work developed a spherical nucleic acid stabilized cage‐type 3D electrochemiluminescence reporter probe for amplification‐free and ultrasensitive detection of pathogenic. Furthermore, a hand‐held detection device was designed, and we established a straightforward workflow enabling sample to answer within 15 min.
Yu Fu +11 more
wiley +1 more source
The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak
Viruses, 2017 Smallpox (variola) virus is considered a Category A bioterrorism agent due to its ability to spread rapidly and the high morbidity and mortality rates associated with infection. Current recommendations recognize the importance of oral antivirals and call
Scott A. Foster +2 more
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The American Journal of Bioethics, 2003 This article reviews the history of smallpox and ethical issues that arise with its threat as a biological weapon. Smallpox killed more people than any infectious disease in history--and perhaps three times more people in the 20th Century than were killed by all the wars of that period.
openaire +3 more sources
Emerging Microbes and InfectionsA large outbreak of monkeypox occurred in 2022, and most people lack immunity to orthopoxvirus. Smallpox vaccination is essential for preventing further smallpox outbreaks.
Hao Liu +7 more
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