Results 31 to 40 of about 125,699 (320)

Remaining Questions about Clinical Variola Major

Emerging Infectious Diseases, 2011
After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
doaj   +1 more source

Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age

Science, 2020
Viking smallpox diversity Humans have a notable capacity to withstand the ravages of infectious diseases. Smallpox killed millions of people but drove Jenner's invention of vaccination, which eventually led to the annihilation of this virus, declared in ...
Barbara Mühlemann, L. Vinner, A. Margaryan, H. Wilhelmson, Constanza de la Fuente Castro, M. Allentoft, Peter de Barros Damgaard, A. Hansen, S. Holtsmark Nielsen, L. Strand, Jan Bill, A. Buzhilova, T. Pushkina, Ceri Falys, V. Khartanovich, V. Moiseyev, M. Jørkov, Palle Østergaard Sørensen, Yvonne Magnusson, Ingrid Gustin, H. Schroeder, G. Sutter, Geoffrey L. Smith, C. Drosten, R. Fouchier, Derek J. Smith, E. Willerslev, T. Jones, M. Sikora   +28 more
semanticscholar   +1 more source

Urban inoculation and the decline of smallpox mortality in eighteenth-century cities-a reply to Razzell. [PDF]

, 2015
Smallpox was probably the single most lethal disease in eighteenth-century Britain but was reduced to a minor cause of death by the mid-nineteenth century due to vaccination programmes post-1798.
Boulton, Jeremy, Davenport, Romola J, Schwarz, Leonard   +2 more
core   +2 more sources

Patterns of smallpox mortality in London, England, over three centuries.

PLoS Biology, 2020
Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control interventions, and the fact that it has been successfully eradicated.
Olga Krylova, David J D Earn
doaj   +1 more source

Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]

, 2004
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan, Oliver WC
core   +2 more sources

Struggling to a monumental triumph : Re-assessing the final stages of the smallpox eradication program in India, 1960-1980 [PDF]

, 2007
The global smallpox program is generally presented as the brainchild of a handful of actors from the WHO headquarters in Geneva and at the agency's regional offices.
Basu, R. N, Bonne W, Bonne W, Brilliant L. B, Brilliant L. B, Dutta Mahendra, Dutta Mahendra, Grasset N, Grasset N, Grasset N, Grasset N, Grasset N, Grasset N. c, Greenough P, Gunaratne V.T.H, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Jungalwalla N.K, Mahler H, Maltseva N, Mani C, Naraindas Harish, Payne A.M.H, Pifer John M, Sanjoy Bhattacharya, Singh Mahendra   +33 more
core   +2 more sources

Reflections on Dr J Michael Lane, a giant of public health (1936-2020)

Global Biosecurity, 2020
Reflections on Dr J Michael Lane (1936-2020) a global leader in smallpox eradication and the Director of Smallpox Eradication at the US CDC. Dr Lane was an alumnus of the US CDC's Epidemic Intelligence Service and had worked in global health on control ...
C Raina MacIntyre
doaj   +1 more source

Drug Development against Smallpox: Present and Future

Antimicrobial Agents and Chemotherapy, 2020
Forty years after the last endemic smallpox case, variola virus (VARV) is still considered a major threat to humans due to its possible use as a bioterrorism agent.
D. Delaune, F. Iseni
semanticscholar   +1 more source

Efficacy of CMX001 as a Prophylactic and Presymptomatic Antiviral Agent in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

Viruses, 2011
CMX001, a lipophilic nucleotide analog formed by covalently linking 3‑(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox.
Richard W. Moyer, George Painter, Randall Lanier, Amanda D. Rice, Scott Foster, Bernhard Lampert, Mathew M. Adams, Alice Robertson   +7 more
doaj   +1 more source

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG, de Quadros, CA, Dowdle, WR, Foege, WH, Henderson, DA, John, TJ, Levine, MM   +6 more
core   +1 more source