BMC Microbiology, 2021 Background Anthrax and smallpox are high-risk infectious diseases, and considered as potential agents for bioterrorism. To develop an effective countermeasure for these diseases, we constructed a bivalent vaccine against both anthrax and smallpox by ...
Deok Bum Park +9 more
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Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design
Biomedicines, 2021 Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic ...
Onur Kaynarcalidan +2 more
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Possible Mpox Protection from Smallpox Vaccine-Generated Antibodies among Older Adults. [PDF]
Emerg Infect Dis, 2023 Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71–80 years of age.
Sanz-Muñoz I +9 more
europepmc +2 more sources
Safety and Efficacy of Post-Eradication Smallpox Vaccine as an Mpox Vaccine: A Systematic Review with Meta-Analysis. [PDF]
Int J Environ Res Public Health, 2023 According to the World Health Organization, 83,339 laboratory-confirmed cases, including 72 deaths, of mpox (formerly known as monkeypox), have been reported from 110 locations globally as of 20 December 2022, making the disease a public health concern ...
Malone SM +8 more
europepmc +2 more sources
Monkeypox in Patient Immunized with ACAM2000 Smallpox Vaccine During 2022 Outbreak. [PDF]
Emerg Infect Dis, 2022 We report a case of monkeypox in the United States in a patient who had been vaccinated with ACAM2000 smallpox vaccine 8 years earlier. Despite his vaccination status, he still contracted disease.
Turner M +5 more
europepmc +2 more sources
Mpox outbreak in the Netherlands, 2022: public health response, characteristics of the first 1,000 cases and protection of the first-generation smallpox vaccine. [PDF]
Euro Surveill, 2023 In early May 2022, a global outbreak of mpox started among persons without travel history to regions known to be enzootic for monkeypox virus (MPXV). On 8 August 2022, the Netherlands reported its 1,000th mpox case, representing a cumulative incidence of
van Ewijk CE +22 more
europepmc +2 more sources
ACAM2000™: The new smallpox vaccine for United States Strategic National Stockpile
Drug Design, Development and Therapy, 2010 Aysegul Nalca, Elizabeth E ZumbrunCenter for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, MD, USAAbstract: Smallpox was eradicated more than 30 years ago, but heightened concerns over ...
Aysegul Nalca, Elizabeth E Zumbrun
doaj +3 more sources
Proteomic assessment of humoral immune responses in smallpox vaccine recipients. [PDF]
Vaccine, 2022 Kennedy RB +4 more
europepmc +2 more sources
A History of Smallpox Vaccination in Modern China: Vaccine Techniques, Instruments, and Localization [PDF]
Uisahak, 2023 This paper examines how smallpox vaccination has been implemented in China from a technological perspective. It is an attempt not only to investigate the impact of technology and instruments on medical advances, but also to deepen the understanding of ...
Jeongeun JO
doaj +1 more source
Live Vaccinia Virus-Coated Microneedle Array Patches for Smallpox Vaccination and Stockpiling
Pharmaceutics, 2021 Although smallpox has been eradicated globally, the potential use of the smallpox virus in bioterrorism indicates the importance of stockpiling smallpox vaccines.
In-Jeong Choi +5 more
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