Results 21 to 30 of about 598,726 (234)

Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review

Reviews in Medical Virology, 2023
Monkeypox is an emerging threat to humans since a new outbreak in May 2022. It is hypothesised that increasing the immunologically naive population after the cessation of the smallpox vaccination campaign in the 1980s is one of the leading causes of it ...
Fahima Akter, Tahira Binte Hasan, Farhana Alam, Aurpy Das, Shanta Afrin, Sadia Maisha, A. Masud, Saif-Ur-Rahman Km   +7 more
semanticscholar   +1 more source

Low-Temperature Multiple Micro-Dispensing on Microneedles for Accurate Transcutaneous Smallpox Vaccination

Vaccines, 2022
Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim, Yun-Ho Hwang, Seonyeong An, Keum-Yong Seong, Seo-Yeon Kim, Semin Kim, Hyeseon Lee, Kang-Oh Lee, Mi-Young Kim, Dokeun Kim, You-Jin Kim, Seung-Yun Yang   +11 more
doaj   +1 more source

Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022

MMWR. Morbidity and mortality weekly report, 2022
Certain laboratorians and health care personnel can be exposed to orthopoxviruses through occupational activities. Because orthopoxvirus infections resulting from occupational exposures can be serious, the Advisory Committee on Immunization Practices ...
A. Rao, B. Petersen, F. Whitehill, J. Razeq, S. Isaacs, M. J. Merchlinsky, D. Campos-Outcalt, Rebecca L Morgan, I. Damon, Pablo J. Sánchez, B. Bell   +10 more
semanticscholar   +1 more source

Development of a Multi-Epitope Universal mRNA Vaccine Candidate for Monkeypox, Smallpox, and Vaccinia Viruses: Design and In Silico Analyses

Viruses, 2023
Notwithstanding the presence of a smallpox vaccine that is effective against monkeypox (mpox), developing a universal vaccine candidate against monkeypox virus (MPXV) is highly required as the mpox multi-country outbreak has increased global concern ...
N. Rcheulishvili, J. Mao, Dimitri Papukashvili, Shunping Feng, Cong Liu, Xidan Yang, Jihui Lin, Yunjiao He, Peng George Wang   +8 more
semanticscholar   +1 more source

Early smallpox vaccine manufacturing in the United States: Introduction of the "animal vaccine" in 1870, establishment of "vaccine farms", and the beginnings of the vaccine industry.

Vaccine, 2020
Esparza J, Lederman S, Nitsche A, Damaso CR.   +3 more
europepmc   +2 more sources

Immunomodulator-based enhancement of anti smallpox immune responses. [PDF]

PLoS ONE, 2015
BACKGROUND:The current live vaccinia virus vaccine used in the prevention of smallpox is contraindicated for millions of immune-compromised individuals. Although vaccination with the current smallpox vaccine produces protective immunity, it might result ...
Osmarie Martínez, Eric Miranda, Maite Ramírez, Saritza Santos, Carlos Rivera, Luis Vázquez, Tomás Sánchez, Raymond L Tremblay, Eddy Ríos-Olivares, Miguel Otero   +9 more
doaj   +1 more source

Multi-epitope mRNA Vaccine Design that Exploits Variola Virus and Monkeypox Virus Proteins for Elicitation of Long-lasting Humoral and Cellular Protection Against Severe Disease

Journal of Medical Science, 2022
Human monkeypox represents a relatively underexplored infection that has received increased attention since the reported outbreak in May 2022. Due to its clinical similarities with human smallpox, this virus represents a potentially tremendous health ...
Dženan Kovačić, Adna Salihović
doaj   +1 more source

Prevention and Treatment of Monkeypox: A Systematic Review of Preclinical Studies

Viruses, 2022
The outbreak of monkeypox, coupled with the onslaught of the COVID-19 pandemic is a critical communicable disease. This study aimed to systematically identify and review research done on preclinical studies focusing on the potential monkeypox treatment ...
Nurizzati Sudarmaji, Nurolaini Kifli, Andi Hermansyah, Siang Fei Yeoh, Bey-Hing Goh, Long Chiau Ming   +5 more
doaj   +1 more source

Beyond the myths: Novel findings for old paradigms in the history of the smallpox vaccine. [PDF]

PLoS Pathog, 2018
1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, 2 Centre for Biological Threats and Special Pathogens 1 –Highly Pathogenic Viruses & German Consultant Laboratory for Poxviruses ...
Esparza J, Nitsche A, Damaso CR.
europepmc   +2 more sources

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections

Viruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj   +1 more source