Results 191 to 200 of about 16,449 (234)

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

NCOR1 and NCOR2 Exhibit Distinct Cellular and Transcriptomic Signatures in Human Abdominal Aortic Aneurysm. [PDF]

Biomedicines
Pelisek J, Yundung Y, Menges AL, Rössler F, Reutersberg B, Zimmermann A, Geiger M.   +6 more
europepmc   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

It's not me, it's you: Anti-phage nuclease specificity inside a bacterium. [PDF]

PLoS Pathog
Hong A, Bondy-Denomy J.
europepmc   +1 more source

Focal adhesion proteins confer smooth muscle anoikis resistance and protection against aortic aneurysm and dissection. [PDF]

JCI Insight
Zhu Z, Liu M, Wei J, Suryanarayan D, Behzadi P, Edgar R, Phillippi JA, St Hilaire C, Espinosa-Diez C, Gomez D.   +9 more
europepmc   +1 more source

DNA actively regulates the "safety-belt" dynamics of condensin during loop extrusion. [PDF]

Nat Commun
Chen J, Feng C, Wang Y, Chu X.
europepmc   +1 more source

Study of Bending Strength Detection Method for SMC Composites Based on Laser-Induced Breakdown Spectroscopy. [PDF]

Materials (Basel)
Wang H, Gao M, Qiao Z, Li J, Cui X, Wang X.   +5 more
europepmc   +1 more source

Decoding Mitotic Chromosome Assembly: Three Rules Governing Condensin-Cohesin Engagement. [PDF]

Research (Wash D C)
Yan H, Zhou X, Wang F.
europepmc   +1 more source