Results 181 to 190 of about 16,449 (234)

From Tweets to Tyranny: Exploring the Symmetry Between State and Social Media Censorship of Speech

Journal of Social Philosophy, EarlyView.
Bhanuraj Kashyap, Paul Formosa
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Structural and mechanistic perspectives on Nse5/6 regulation of the Smc5/6 complex. [PDF]

Front Mol Biosci
Kim JH, Rao DR, Kim KD.
europepmc   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Allelic Analysis of <i>smc-6</i> Reveals Domain-Specific Roles in DNA Repair in <i>Caenorhabditis elegans</i>. [PDF]

Int J Mol Sci
Liang Y, Zhang Y, Xie J, Xiao Q, Liao G, Lu J.   +5 more
europepmc   +1 more source

Novel volume‐electron microscopic ultrastructural analysis of gastrointestinal excitability associated with calcium–activated chloride channels

The Journal of Physiology, EarlyView.
Abstract figure legend Immunohistochemistry, electrophysiology and pharmacology are useful tools for understanding protein and channel expression and physiological reactions of calcium‐activated chloride channels (CaCCs). Conventional transmission electron microscopy has provided useful 2‐D information on organelle arrangement, localization and ...
Hiromi Tamada
wiley   +1 more source

The 3D genomics of lampbrush chromosomes highlights the role of active transcription in chromatin organization. [PDF]

Nucleic Acids Res
Lagunov T, Gridina M, Nurislamov A, Kulikova T, Maslova A, Konstantinov V, Popov A, Krasikova A, Fishman V.   +8 more
europepmc   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Comparison of Alkyl-Bridged Bis(N-Heterocyclic Carbene) Nickel Precatalysts: Structure and Catalytic Activity in the Reductive Cleavage and Suzuki-Miyaura Reactions. [PDF]

ACS Omega
Zhang CS, Beams EC, Moffett AL, Luo C, McMillen CD, Chianese AR, Green KA.   +6 more
europepmc   +1 more source