Results 181 to 190 of about 16,909 (206)

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Multi-subunit collaboration enables Smc5/6 to function as a composite SUMO E3 complex. [PDF]

Nat Commun
Xue X, Fan J, Li S, Ignatyeva S, Gallegos-Elias P, McEntire-Benitez H, Zhu X, Kar TR, Epps J, Eliaz L, Holland K, Romero A, Zhao X.   +12 more
europepmc   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

The 3D genomics of lampbrush chromosomes highlights the role of active transcription in chromatin organization. [PDF]

Nucleic Acids Res
Lagunov T, Gridina M, Nurislamov A, Kulikova T, Maslova A, Konstantinov V, Popov A, Krasikova A, Fishman V.   +8 more
europepmc   +1 more source

Research Progress on the Molecular Mechanism of LRP1 and TGFβ-PDGFRβ Signaling Network in Atherosclerosis and Vascular Remodeling. [PDF]

Int J Mol Sci
Guo X, Xue S, Wang Q, Chen X, Yang J, Zhou Y, Zhang Y, Niu W.   +7 more
europepmc   +1 more source

Comparison of Alkyl-Bridged Bis(N-Heterocyclic Carbene) Nickel Precatalysts: Structure and Catalytic Activity in the Reductive Cleavage and Suzuki-Miyaura Reactions. [PDF]

ACS Omega
Zhang CS, Beams EC, Moffett AL, Luo C, McMillen CD, Chianese AR, Green KA.   +6 more
europepmc   +1 more source

Condensin chromatin association is regulated by SMC head and hinge engagement and phosphorylation

Miles CA, Yu M, Minchell NE, Schalbetter SA, Oliver AW, Sweet SM, Baxter J.   +6 more
europepmc   +1 more source

Cryo-EM and single molecule visualization unravel the role of human condensin II activation by M18BP1 in driving DNA compaction

Borsellini A, Chamera S, Cecatiello V, Andrecka J, Vannini A.   +4 more
europepmc   +1 more source

Single Domain Antibody Inhibitors Target the Coiled Coil Arms of the Bacillus subtilis SMC complex

Gosselin O, Taschner M, Huber-Hürlimann LM, Seeger MA, Gruber S.   +4 more
europepmc   +1 more source