Results 211 to 220 of about 16,449 (234)
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THE STRUCTURE AND FUNCTION OF SMC AND KLEISIN COMPLEXES
Annual Review of Biochemistry, 2005▪ Abstract Protein complexes consisting of structural maintenance of chromosomes (SMC) and kleisin subunits are crucial for the faithful segregation of chromosomes during cell proliferation in prokaryotes and eukaryotes. Two of the best-studied SMC complexes are cohesin and condensin.
Kim Nasmyth, Christian Haering
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The maintenance of chromosome structure: positioning and functioning of SMC complexes
Nature Reviews Molecular Cell Biology, 2014Structural maintenance of chromosomes (SMC) complexes, which in eukaryotic cells include cohesin, condensin and the Smc5/6 complex, are central regulators of chromosome dynamics and control sister chromatid cohesion, chromosome condensation, DNA replication, DNA repair and transcription.
Camilla Sjögren +2 more
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Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair
Chromosome Research, 2009Bacteria and archaea possess several different SMC-like proteins, which perform essential functions in a variety of chromosome dynamics, such as chromosome compaction, segregation, and DNA repair. SMC-like proteins localize to distinct sites within the cells at different time points in the cell cycle, or are recruited to sites of DNA breaks and damage.
Graumann, Peter, Knust, Tobias
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Structural and Functional Features of Bacterial SMC Complexes
Цитология, 2023SMC complexes (Structural maintenance of chromosomes) are key participants in the spatial organization of DNA in all living organisms – in bacteria, archaea and eukaryotes. In bacteria, there are several homologues of SMC complexes that perform seemingly unrelated functions, but function through very similar, highly conserved mechanisms.
N. E. Morozova +2 more
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SMC Complexes: Universal DNA Looping Machines with Distinct Regulators
Trends in Genetics, 2018What drives the formation of chromatin loops has been a long-standing question in chromosome biology. Recent work provides major insight into the basic principles behind loop formation. Structural maintenance of chromosomes (SMC) complexes, that are conserved from bacteria to humans, are key to this process.
Benjamin Rowland
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SMC Complexes--Wrapped Up in Controversy
Science, 2003SMC proteins regulate key chromosomal events during cell division. In their Perspective, [Milutinovich and Koshland][1] discuss several papers published here ([ Kitajima et al .][2]) and elsewhere that elucidate how SMC proteins, in complexes with their binding partners, bind to chromatin to carry out their many functions.
Mark Milutinovich, Douglas E. Koshland
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Complex temperature dependence of the dielectric response in simple SmC* phases
Soft Matter, 2023In the case of polar smectic liquid crystals, as an example of a soft material, it is shown that what is valid for stable structures cannot be extended to the analysis of dynamics straightforwardly.
Dina Jukić, Mojca Čepič
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SMC Protein Complexes and the Maintenance of Chromosome Integrity
2003Structural maintenance of chromosomes (SMC) family proteins have attracted much attention for their unique protein structure and critical roles in mitotic chromosome organization. Elegant genetic and biochemical studies in yeast and Xenopus identified two different SMC heterodimers in two conserved multiprotein complexes termed 'condensin' and 'cohesin'
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SMC protein complexes and higher-order chromosome dynamics
Current Opinion in Cell Biology, 1998The structural maintenance of chromosome (SMC) family of proteins represents an expanding group of chromosomal ATPases that are highly conserved among Bacteria, Archaea and Eukarya. During the past year, significant progress has been made towards understanding the cellular functions and molecular activities of this new class of proteins.
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DNA renaturation activity of the SMC complex implicated in chromosome condensation
Nature, 1997Chromosome condensation occurs in mitosis before the separation of sister chromatids, and requires DNA topoisomerase II and a group of proteins called SMCs. The resulting condensed chromosomes in metaphase have a complex hierarchical structure. SMCs, the components of condensed chromosomes, are also required for the separation of sister chromatids and ...
T, Sutani, M, Yanagida
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