Results 111 to 120 of about 49,437 (364)
Estimation, Analysis and Smoothing of Self-Similar Network Induced Delays in Feedback Control of Nuclear Reactors [PDF]
This paper analyzes a nuclear reactor power signal that suffers from network induced random delays in the shared data network while being fed-back to the Reactor Regulating System (RRS).
Das, Saptarshi+5 more
core +2 more sources
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
Controlled thinning and surface smoothening of silicon nanopillars [PDF]
A convenient method has been developed to thin electron beam fabricated Silicon nanopillars under controlled surface manipulation by transforming the surface of the pillars to an oxide shell layer followed by the growth of sacrificial ammonium silicon fluoride coating.
Kalem, S.+6 more
openaire +5 more sources
Silicon carbide (SiC) can be tribo-chemically smoothened during a self-mated sliding procedure in the aqueous environment. As well reported in the point-contact tests, this smoothening process works well due to the abundant water as oxidant.
Le Jin+4 more
doaj +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Cilia-Mediated Hedgehog Signaling in Drosophila
Cilia mediate Hedgehog (Hh) signaling in vertebrates and Hh deregulation results in several clinical manifestations, such as obesity, cognitive disabilities, developmental malformations, and various cancers.
Anujaianthi Kuzhandaivel+3 more
doaj +1 more source
Residue 6.43 defines receptor function in class F GPCRs
The class Frizzled of G protein-coupled receptors (GPCRs) consist of ten Frizzled (FZD1-10) subtypes and Smoothened (SMO). Here the Schulte laboratory demonstrates that FZDs differ substantially from SMO in receptor activation-associated conformational ...
Ainoleena Turku+4 more
doaj +1 more source
Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K [PDF]
SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric Gi proteins in many cell types, including cardiomyocytes.
Al-Owais, Moza+6 more
core +1 more source
Persistent currents in a Bose-Einstein condensate in the presence of disorder
We examine bosonic atoms that are confined in a toroidal, quasi-one-dimensional trap, subjected to a random potential. The resulting inhomogeneous atomic density is smoothened for sufficiently strong, repulsive interatomic interactions.
A.D. Jackson+34 more
core +1 more source
The mechanisms that restrict regeneration and maintain cell identity following injury are poorly characterized in higher vertebrates. Following β-cell loss, 1–2% of the glucagon-producing α-cells spontaneously engage in insulin production in mice.
V. Cigliola+16 more
semanticscholar +1 more source