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Paudel BB, Tan S-F, Fox TE, et al. Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood Adv. 2024;8(5):1137-1142. [PDF]
Blood Adveuropepmc +1 more source
Upregulation of smpd3 via BMP2 stimulation and Runx2 [PDF]
BMB Reports, 2009 Deletion of smpd3 induces osteogenesis and dentinogenesis imperfecta in mice. smpd3 is highly elevated in the parietal bones of developing mouse calvaria, but not in sutural mesenchymes.
Hyun-Mo Ryoo, Jae-Young Kim, Je-Yoel Cho
exaly +1 more source
SMPD3 deficiency perturbs neuronal proteostasis and causes progressive cognitive impairment
Cell Death and Disease, 2018 Neutral sphingomyelinase smpd3 is most abundantly expressed in neurons of brain. The function of SMPD3 has remained elusive. Here, we report a pathogenetic nexus between absence of SMPD3 in the Golgi compartment (GC) of neurons of the smpd3-/- mouse ...
Susanne Brodesser +2 more
exaly +2 more sources
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Role of SMPD3 during Bone Fracture Healing and Regulation of Its Expression
Molecular and Cellular Biology, 2019Pierre Moffatt +2 more
exaly
Inducible transient expression of Smpd3 prevents early lethality in fro/fro mice
Genesis, 2014Monzur Murshed, Zohreh Khavandgar
exaly
Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development
Proceedings of the National Academy of Sciences of the United States of America, 2005Wilhelm Stoffel
exaly