Results 71 to 80 of about 1,974 (156)
The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network [PDF]
Scientific Reports, 2019 ABSTRACT The coordinated expression of myogenic regulatory factors, including MyoD and myogenin, orchestrates the steps of skeletal muscle development, from myoblast proliferation and cell-cycle exit, to myoblast fusion and myotubes maturation.
Codato, Roberta +7 more
openaire +2 more sources
Advanced Science, Volume 12, Issue 46, December 11, 2025.Protein arginine methyltransferase 3 (PRMT3) induces the arginine methylation of Y‐box binding protein 1 (YBX1), which suppresses phase separation and is imperative for its nuclear translocation. Subsequently, lysine‐specific demethylase 4A demethylates YBX1 to unmask the R247 residue and promote its phase separation, which transcriptionally regulates ...
Yunxing Shi +11 more
wiley +1 more source
MedComm, Volume 6, Issue 10, October 2025.Hypertrophic scars and keloids highlight distinct epidemiology, multifactorial triggers (genetic, mechanical, medical), and dysregulated signaling hubs (TGF‐β, Integrin‐FAK, Wnt/β‐catenin). Emerging interventions targeting fibroblast plasticity, inflammation, and biomechanics via gene editing, immune modulation, and biomaterials are increasingly ...
Xiaowan Fang +7 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2021 Background Castration-resistant prostate cancer (CRPC) is associated with a very poor prognosis, and the treatment of which remains a serious clinical challenge.
Shangwei Zhong +7 more
doaj +1 more source
Enhanced SMYD3 expression is essential for the growth of breast cancer cells [PDF]
Cancer Science, 2006 We previously reported that upregulation of SMYD3, a histone H3 lysine‐4‐specific methyltransferase, plays a key role in the proliferation of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). In the present study, we reveal that SMYD3 expression is also elevated in the great majority of breast cancer tissues.
Ryuji, Hamamoto +6 more
openaire +2 more sources
Blue‐Gray Papules on the Chest and Face
JEADV Clinical Practice, Volume 5, Issue 1, Page 326-329, March 2026.
Sanjana Likki +5 more
wiley +1 more source
Exploration of Biomarkers of Food Intake in a Caribbean Hispanic Population
Molecular Nutrition &Food Research, Volume 69, Issue 20, October 2025.Validated BFIs show significant associations with food intake in an observational setting, and those associations were often modulated by non‐dietary factors. The identification of genotype‐BFI associations implies that the utility of a BFI could depend on common genetic differences.
Laurence D. Parnell +8 more
wiley +1 more source
Cell Death and Disease, 2021 Abnormal expression of long-noncoding RNA is involved in the tumorigenesis and progression of various cancers, but the potential molecular regulatory mechanisms are unclear.
Mo Liu +14 more
doaj +1 more source
MedComm, Volume 6, Issue 8, August 2025.Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao +7 more
wiley +1 more source
Journal of Hepatocellular Carcinoma, 2023 Jin Sun,1– 3 Yingnan Li,1– 3 Mengjiao Shi,1,2 Hongwei Tian,1– 3 Jun Li,1– 3 Kai Zhu,1– 3 Ying Guo,1– 3 Yanhua Mu,1– 3 Jing Geng,1– 3 Zongfang Li1– 4 1National-Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, Xi’an Jiaotong ...
Sun J +9 more
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