Results 81 to 90 of about 51,201 (249)

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Efficacy and Limitations of Chemically Diverse Small-Molecule Enzyme-Inhibitors against the Synergistic Coagulotoxic Activities of Bitis Viper Venoms

Molecules, 2022
Snakebite remains a significant public health burden globally, disproportionately affecting low-income and impoverished regions of the world. Recently, researchers have begun to focus on the use of small-molecule inhibitors as potential candidates for ...
Nicholas J. Youngman, Matthew R. Lewin, Rebecca Carter, Arno Naude, Bryan G. Fry   +4 more
doaj   +1 more source

Serum Proteinogram in the Free‐Living Brazilian Common Opossum (Didelphis aurita)

ELECTROPHORESIS, Volume 46, Issue 18, Page 1447-1454, September 2025.
ABSTRACT Didelphis aurita is a synanthropic marsupial widely distributed in southeastern Brazil, known for its resistance to venom and its relevance in biomedical research. This study aimed to characterize the serum proteinogram of free‐living D. aurita individuals.
Andrés Mauricio Ortega Orozco, Lucas Drumond Bento, Pollyanna Cordeiro Souto, Fabrícia Modolo Girardi, Verônica Rodrigues Castro, João Vitor Gonçalves de Oliveira, Camilo José Ramirez Lopez, Edvaldo Barros, Artur Kanadani Campos, Leandro Abreu da Fonseca   +9 more
wiley   +1 more source

Effects of Bothrops asper snake venom on lymphatic vessels: insights into a hidden aspect of envenomation. [PDF]

PLoS Neglected Tropical Diseases, 2008
Envenomations by the snake Bothrops asper represent a serious medical problem in Central America and parts of South America. These envenomations concur with drastic local tissue pathology, including a prominent edema. Since lymph flow plays a role in the
Javier Mora, Rodrigo Mora, Bruno Lomonte, José María Gutiérrez   +3 more
doaj   +1 more source

Enzymatic Analysis of Iranian Echis carinatus Venom Using Zymography [PDF]

, 2017
Snakebite is a common problem especially in tropical areas all over the world including Iran. Echis carinatus as one of the most dangerous Iranian snakes is spreading in this country excluding central and northwest provinces.
Hoseiny, Seyed Mehdi, Kamyab, Mostafa, Kim, Euikyung, Seyedian, Ramin   +3 more
core  

Transcriptomic basis for an antiserum against Micrurus corallinus (coral snake) venom [PDF]

, 2009
Background Micrurus corallinus (coral snake) is a tropical forest snake belonging to the family Elapidae. Its venom shows a high neurotoxicity associated with pre- and post-synaptic toxins, causing diaphragm paralysis, which may result in death. In spite
Luciana I Leão, Paulo L Ho, Inacio de LM Junqueira-de-Azevedo   +2 more
core   +2 more sources

Proteomic profiling of snake venom metalloproteinases (SVMPs): Insights into venom induced pathology

Toxicon, 2009
Bothrops sp. snakebites account for the majority of envenomations in South and Central America. Bothrops jararaca accidents are characterized by edema, hemorrhage and necrosis, mainly attributed to the action of hemorrhagic snake venom metalloproteinases (SVMPs).
Renata M S, Terra, Antônio F M, Pinto, Jorge A, Guimarães, Jay W, Fox   +3 more
openaire   +2 more sources

Quantum Chemical, Spectroscopic and In Silico (Molecular Docking, Molecular Dynamic and ADME) Studies on Anti‐Aging Pentapeptide‐3 (Vialox)

International Journal of Quantum Chemistry, Volume 125, Issue 15, August 5, 2025.
This study investigates the anti‐aging potential of Pentapeptide‐3 (Vialox) using quantum chemical, spectroscopic, and in silico methods. Molecular docking and dynamics analysis confirm its stable interactions with key aging‐related receptors, highlighting Pentapeptide‐3 as a promising candidate for cosmeceutical applications targeting skin aging ...
Dilan Akhan, Bilge Bicak, Serda Kecel Gunduz, Elif Akalin   +3 more
wiley   +1 more source

Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox.
V Núñez Rangel, M Fernández Culma, P Rey-Suárez, JA Pereañez   +3 more
doaj   +1 more source

Echis carinatus Snakebite, a Rare Fatal Envenomation Incident in a Young Pakistani Boy: Case Report

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Prompt identification and aggressive intervention in Echis carinatus envenomation are paramount to avert life‐threatening complications such as venom‐induced consumptive coagulopathy (VICC), acute renal failure (ARF), and necrotizing fasciitis.
Farina Fatima Siddiqui, Aisha Rehman Siddiqui, Kundan Kumar Maheshwari, Khizer Mehmood, Jaint Kumar, Noor‐Us‐Sahar Siddiqui, Muhammad Momin Khan, Sania Javed, Alaa Jlailati   +8 more
wiley   +1 more source