Results 71 to 80 of about 34,979 (216)
Snakebite remains a significant public health burden globally, disproportionately affecting low-income and impoverished regions of the world. Recently, researchers have begun to focus on the use of small-molecule inhibitors as potential candidates for ...
Nicholas J. Youngman +4 more
doaj +1 more source
Number of Pages: 17Integrative BiologyGeological ...
Beaman, Kent R., Dugan, Eric A.
core +1 more source
Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar +2 more
wiley +1 more source
First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases. [PDF]
Adamalysin II, a 24 kDa zinc endopeptidase from the snake venom of Crotalus adamanteus, is a member of a large family of metalloproteinases isolated as small proteinases or proteolytic domains of mosaic haemorrhagic proteins from various snake venoms. Homologous domains have recently been detected in multimodular mammalian reproductive tract proteins ...
F X, Gomis-Rüth, L F, Kress, W, Bode
openaire +2 more sources
Dabsylated Bradykinin Is Cleaved by Snake Venom Proteases from Echis ocellatus
The vasoactive peptide bradykinin (BK) is an important member of the renin–angiotensin system. Its discovery is tightly interwoven with snake venom research, because it was first detected in plasma following the addition of viper venom.
Julius Abiola +4 more
doaj +1 more source
Effects of Bothrops asper snake venom on lymphatic vessels: insights into a hidden aspect of envenomation. [PDF]
Envenomations by the snake Bothrops asper represent a serious medical problem in Central America and parts of South America. These envenomations concur with drastic local tissue pathology, including a prominent edema. Since lymph flow plays a role in the
Javier Mora +3 more
doaj +1 more source
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) [PDF]
Venom is a known source of novel antimicrobial natural products. The substantial, increasing number of these discoveries have unintentionally culminated in the misconception that venom and venom-producing glands are largely sterile environments.
Adams, Rachelle M.M. +13 more
core +1 more source
Coral Venom and Toxins as Protection Against Crown‐of‐Thorns Sea Star Attack
ABSTRACT Crown‐of‐thorns sea star (CoTS) outbreaks are a main cause of hard coral cover decline across the Indo‐Pacific, posing a major threat to the resilience of coral reefs. However, the drivers underlying CoTS feeding on preferred (e.g., Acropora species) versus non‐preferred (e.g., Porites species) are poorly understood. We hypothesised that coral
Lucy M. Gorman +4 more
wiley +1 more source
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox.
V Núñez Rangel +3 more
doaj +1 more source
Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A [PDF]
Background It has been recognized that phospholipase A2 (PLA2) is a crucial component of snake venom, which contributes greatly to snake venom induced inflammation in man. However, the mechanisms through which N49 PLA2 provoke inflammation remain unclear.
Ji-Fu Wei +3 more
core +2 more sources

