Results 51 to 60 of about 127,375 (121)

Blood flow is required for rapid endothelial cell damage induced by a snake venom hemorrhagic metalloproteinase [PDF]

, 2006
The effects of blood flow interruption on the ultrastructural alterations induced by a snake venom hemorrhagic metalloproteinase on skeletal muscle capillary endothelial cells were studied. Saline solution or the metalloproteinase BaP1, from the venom of
Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Gutiérrez, José María, Núñez, Javier   +3 more
core   +1 more source

Dabsylated Bradykinin Is Cleaved by Snake Venom Proteases from Echis ocellatus

Biomedicines
The vasoactive peptide bradykinin (BK) is an important member of the renin–angiotensin system. Its discovery is tightly interwoven with snake venom research, because it was first detected in plasma following the addition of viper venom.
Julius Abiola, Anna Maria Berg, Olapeju Aiyelaagbe, Akindele Adeyi, Simone König   +4 more
doaj   +1 more source

Crystal structure and functional characterization of an Asp49 phospholipase A2 from the bushmaster (Lachesis muta)

Acta Crystallographica Section F, Volume 82, Issue 5, Page 150-159, May 2026.
The crystal structure of an Asp49 phospholipase A2 from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.Snake‐venom phospholipases A2 (PLA2s) are small, structurally conserved enzymes that contribute significantly to the pathophysiology of ...
Noelia Erika Neyra Chama, Frey Francisco Romero Vargas, Eloy Condori Mamani, Jhon Antoni Vargas, Adriano Alves Furtado, Humberto D'Muniz Pereira, Ronald Demetrio Navarro Oviedo, Richard Charles Garratt, José Luis Javier Vega Ramírez, Diego Antonio Leonardo   +9 more
wiley   +1 more source

Effects of Bothrops asper snake venom on lymphatic vessels: insights into a hidden aspect of envenomation. [PDF]

PLoS Neglected Tropical Diseases, 2008
Envenomations by the snake Bothrops asper represent a serious medical problem in Central America and parts of South America. These envenomations concur with drastic local tissue pathology, including a prominent edema. Since lymph flow plays a role in the
Javier Mora, Rodrigo Mora, Bruno Lomonte, José María Gutiérrez   +3 more
doaj   +1 more source

Efficacy and Limitations of Chemically Diverse Small-Molecule Enzyme-Inhibitors against the Synergistic Coagulotoxic Activities of Bitis Viper Venoms

Molecules, 2022
Snakebite remains a significant public health burden globally, disproportionately affecting low-income and impoverished regions of the world. Recently, researchers have begun to focus on the use of small-molecule inhibitors as potential candidates for ...
Nicholas J. Youngman, Matthew R. Lewin, Rebecca Carter, Arno Naude, Bryan G. Fry   +4 more
doaj   +1 more source

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system

Heliyon
Snake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong, Cai-E Wang, Ya-Nan Li, Qi-Yun Zhang, Qian-Yun Sun   +4 more
doaj   +1 more source

Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox.
V Núñez Rangel, M Fernández Culma, P Rey-Suárez, JA Pereañez   +3 more
doaj   +1 more source

The Genetic Basis of Color Polymorphism in the Orb‐Web Spider Gasteracantha cancriformis

Ecology and Evolution, Volume 16, Issue 3, March 2026.
This study investigates the genetic basis of coloration in the polymorphic spider Gasteracantha cancriformis using RNA‐seq data from different female color morphs. We assembled a reference transcriptome and identified differentially expressed genes associated with known pigmentation pathways, including carotenoids, melanin, ommochromes, and pteridines.
Paula Torres‐Quintero, Carolina Pardo‐Díaz, Fabian Salgado‐Roa, Camilo Salazar   +3 more
wiley   +1 more source

snake venom

, 2005
In order to study the role of neutrophils in the acute local pathological alterations induced by Bothrops jararaca snake venom, and in the process of skeletal muscle regeneration that follows, an experimental model was developed in mice pretreated with ...
Cristina M. Fernandes, Zuliani, JP, Juliana P. Zuliani, Zuliani J.P., Irene Fernandes, Fernandes I., Zamunér, Stella Regina, Fernando Chaves, Teixeira C.F.P., Cruz-Hofling M.A., Chaves, F, Teixeira, CFP, Gutierrez, JM, Fernandes, CM, Fernandes, I, Teixeira, Catarina de Fátima, Zamuner S.R., Chaves F., Chaves Mora, Fernando, Fernandes, Irene, Cruz Höfling, Maria Alice, Zuliani, Juliana Pavan, José María Gutiérrez, Catarina F. P. Teixeira, Zamuner, SR, Fernandes, Cristina Maria, Stella R. Zamunér, Gutierrez J.M., María Alice Cruz‐Hofling, Gutiérrez, José María, Fernandes C.M., Cruz-Hofling, MA   +31 more
core   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source