Results 41 to 50 of about 127,375 (121)
Venom metalloproteinase activity and Squirrel Inhibition
, 2016 This file includes 1440 rows of snake venom metalloproteinase activity data, where each row is defined by a unique combination of of rattlesnake (Crotalus oreganus) and a ground squirrel (Otospermophilus beecheyi).
Holding, Matthew L. +5 more
core +1 more source
Neurotoxins from Snake Venom [PDF]
, 1998 Found within snake venoms are a variety of toxic and nontoxic proteins. The effects of snake venoms depend on all of the components of that venom. However, the lethal effects are usually related to the most potent toxins found within the venom; the two ...
Tu, Anthony T.
core +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley +1 more source
Snake Venom Metalloproteinases and Their Peptide Inhibitors from Myanmar Russell’s Viper Venom
Toxins, 2016 Russell’s viper bites are potentially fatal from severe bleeding, renal failure and capillary leakage. Snake venom metalloproteinases (SVMPs) are attributed to these effects.
Khin Than Yee +4 more
doaj +1 more source
Toxins, 2023 The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic ...
Eric Wachtel +8 more
doaj +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities
Frontiers in Ecology and Evolution, 2019 Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected.
Cassandra M. Modahl, Stephen P. Mackessy
doaj +1 more source
PLoS Neglected Tropical Diseases, 2020 Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year.
Julien Slagboom +7 more
doaj +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, Volume 2, Issue 2, June 2026.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
VIEW, Volume 7, Issue 3, June 2026.Cancer‐associated fibroblasts exert intricate mechanisms in the progression and metastasis of renal cell carcinoma. Existing studies have validated the relevant mechanisms of three signaling pathways, which hold promising potential as novel therapeutic targets.
Ruiqiang Sun +4 more
wiley +1 more source