Results 31 to 40 of about 34,979 (216)
Biomedicines, 2020 Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number of limitations associated with their efficacy, safety and affordability for use in tropical snakebite ...
Chunfang Xie +6 more
doaj +1 more source
Toxins, 2017 Rhabdophis lateralis, a colubrid snake distributed throughout the continent of Asia, has recently undergone taxonomic revisions. Previously, Rhabdophis lateralis was classified as a subspecies of R. tigrinus (Yamakagashi) until 2012, when several genetic
Yumiko Komori +6 more
doaj +1 more source
Mediators of Inflammation, 2000 The venom of the snake Bothrops asper, the most important poisonous snake in Central America, evokes an inflammatory response, the mechanisms of which are not well characterized. The objectives of this study were to investigate whether B. asper venom and
Sandra H. P. Farsky +6 more
doaj +1 more source
Leucurogin, a new recombinant disintegrin cloned from Bothrops leucurus (white-tailed-jararaca) with potent activity upon platelet aggregation and tumor growth [PDF]
, 2011 Disintegrins and disintegrins-like proteins are able to inhibit platelet aggregation and integrin-mediated cell adhesion. the aim of this study was to produce one disintegrin-like cloned from Bothrops leucurus venom gland and to characterize it regarding
Almeida, M. C. +9 more
core +2 more sources
Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom. [PDF]
, 2014 Attempts to reconstruct the evolutionary history of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes that are paralogous to toxins, and which therefore represent important connectors to ancestral ...
Bastos, Carolina Mancini Val +5 more
core +3 more sources
Toxins, 2020 The karst viper (Vipera ursinii ssp.) favours high-mountain dry grasslands in southern and south-eastern Croatia. It is medically less important than other Vipera species, because of its remote habitat and the very small amount of venom that it injects ...
Maja Lang Balija +6 more
doaj +1 more source
Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom [PDF]
, 2012 Snakebite envenomation is considered a highly relevant public health hazard in South America, having an impact in terms of mortality and morbidity.
Carvalho, Daniela Cajado +6 more
core +2 more sources
Free Energy Calculations on Snake Venom Metalloproteinase BaP1 [PDF]
Chemical Biology & Drug Design, 2012 BaP1 is a snake venom metalloproteinase from the venom of Bothrops asper, showing high structural homology with the catalytic domain of human adamalysins and matrix metalloproteinases. It induces the release of cytokines, like interleukin‐1 and tumor necrosis factor alpha.
Lingott, T. +2 more
openaire +3 more sources
Toxins, 2019 Snake venoms are complex mixtures of toxic proteins encoded by various gene families that function synergistically to incapacitate prey. A huge repertoire of snake venom genes and proteins have been reported, and alternative splicing is suggested to be ...
Tomohisa Ogawa +12 more
doaj +1 more source
Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. [PDF]
, 2018 The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional ...
Bulfone, Tommaso C +5 more
core +2 more sources