Results 31 to 40 of about 127,375 (121)

The effect of a serum containing acetyl hexapeptide‐8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies

International Journal of Cosmetic Science, EarlyView.
The novel serum demonstrates significant anti‐skin aging effects, effectively improving static and dynamic wrinkles and skin texture. Therefore, this formulation holds promise as a safe and effective product in the field of anti‐wrinkle skincare products.
Mingjie Zhu, Xiaofeng He, Zailing Zhu, Stephen Lynch, Hequn Wang, Xiaoyin Zhou, Yidong Tu, Andrew Steel, Kung Chi Hsu, Yueqing Niu, Anna Cho, Mutsue Hashimoto, Xi Yan, Maggie Su, Wenna Wang   +14 more
wiley   +1 more source

Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines

Pharmaceutics, 2023
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration.
Dan E. Vivas-Ruiz, Paola Rosas, Alex Proleón, Daniel Torrejón, Fanny Lazo, Ana Belén Tenorio-Ricca, Francisco Guajardo, Cristopher Almarza, Víctor Andrades, Jessica Astorga, Daniel Oropesa, Jorge Toledo, María Jesús Vera, Jorge Martínez, Ramiro Araya-Maturana, Karen Dubois-Camacho, Marcela A. Hermoso, Valéria G. Alvarenga, Eladio Flores Sanchez, Armando Yarlequé, Luciana Souza Oliveira, Félix A. Urra   +21 more
doaj   +1 more source

Hemoperfusion as Adjunctive Therapy in Severe Snake Envenomation Refractory to Antivenom: A Case Series

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Snake envenomation remains a significant cause of morbidity worldwide, with antivenom serving as the cornerstone of treatment. This case series describes outcomes of three male patients (ages 34–63 years) with severe envenomation who demonstrated progressive local swelling and coagulopathy despite receiving at least 15 vials of antivenom.
Sayed Masoud Hosseini, Shahin Shadnia, Babak Mostafazadeh, Mitra Rahimi, Faraz Zandiyeh, Aida Rabiei Nezhad, Peyman Erfan Talab Evini   +6 more
wiley   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Jacoby-Alner, T.E., Davern, K.M., Swindells, K., Stephens, N., Balmer, L., Brown, S.G.A.   +5 more
core  

Structure of carbohydrate chain of a thrombin-like protease from the venom of Agkistrodon halys brevicaudus stejneger snake [PDF]

, 2009
The structure of the carbohydrate chain of kangshuanmei, a thrombin-like serine protease isolated from Agkistrodon halys brevicaudus stejneger snake venom, was determined. The carbohydrate content of the kangshuanmei was 18%.
Saitou, Kenji, Okada, Tadashi, Sakai, Junichi, Murase, Yutaka, Jangprasert, Panchalee, Nakano, Takahiro, Yamamoto, Chikashi, Rojnuckarin, Ponlapat   +7 more
core   +1 more source

Serum-based inhibition of pitviper venom by eastern indigo snakes (Drymarchon couperi)

Biology Open, 2019
When organisms possess chemical defenses, their predators may eventually evolve resistance to their toxins. Eastern indigo snakes (Drymarchon couperi; EIS) prey on pitvipers and are suspected to possess physiological resistance to their venom.
Scott M. Goetz, Sara Piccolomini, Michelle Hoffman, James Bogan, Matthew L. Holding, Mary T. Mendonça, David A. Steen   +6 more
doaj   +1 more source

Divergent Specialization of Simple Venom Gene Profiles among Rear-Fanged Snake Genera (Helicops and Leptodeira, Dipsadinae, Colubridae)

Toxins, 2022
Many venomous animals express toxins that show extraordinary levels of variation both within and among species. In snakes, most studies of venom variation focus on front-fanged species in the families Viperidae and Elapidae, even though rear-fanged ...
Peter A. Cerda, Jenna M. Crowe-Riddell, Deise J. P. Gonçalves, Drew A. Larson, Thomas F. Duda, Alison R. Davis Rabosky   +5 more
doaj   +1 more source

Immunological Cross‐Reactivity and Neutralizing Efficacy of Antivenom Against Five Medically Important Iranian Viper Venoms

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Investigating Iranian viper venoms reveals compositional and antigenic diversity impacting antivenom efficacy. The study highlights the need to incorporate both broadly cross‐reactive and specifically under‐represented venoms into immunization mixtures to optimize paraspecific protection strategies.
Sedigheh Khamehchian, Fatemeh Tahoori, Hadi Rabie, Nafiseh Nasri Nasrabadi, Majid Tebianian   +4 more
wiley   +1 more source

Structures and Functions of Snake Venom Metalloproteinases (SVMP) from Protobothrops venom Collected in Japan

Molecules, 2017
Snake venom metalloproteinases (SVMP) are widely distributed among the venoms of Crotalinae and Viperidae, and are organized into three classes (P-I, P-II and P-III) according to their size and domain structure.
Etsuko Oyama, Hidenobu Takahashi
doaj   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, Volume 183, Issue 18, Page 5516-5540, September 2026.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source