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Inflammatory effects of snake venom metalloproteinases [PDF]
Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They are relevant in the pathophysiology of envenomation, being responsible for local and systemic hemorrhage frequently observed in the victims.
Catarina de Fátima Pereira Teixeira +3 more
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Processing of Snake Venom Metalloproteinases: Generation of Toxin Diversity and Enzyme Inactivation
Snake venom metalloproteinases (SVMPs) are abundant in the venoms of vipers and rattlesnakes, playing important roles for the snake adaptation to different environments, and are related to most of the pathological effects of these venoms in human victims.
Richard H Valente +1 more
exaly +4 more sources
Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez
Jay W. Fox and José María Gutiérrez recently finished editing a Special Issue on the topic “Snake Venom Metalloproteinases” in Toxins. The Special Issue covers a wide range of topics, including the molecular evolution and structure of snake venom ...
Jay W. Fox, José María Gutiérrez
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The global exploration of snakebites requires the use of quantitative omics approaches to characterize snake venom as it enters into the systemic circulation.
Nicholas Kevin Willard +11 more
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Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C. Offor +2 more
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There is a strong correlation between the composition of Deinagkistrodon acutus venom proteins and their potential pharmacological effects. The proteomic analysis revealed 103 proteins identified through label-free proteomics from 30 different snake ...
Jin Huang +4 more
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Snake envenomations constitute a worldwide neglected tropical disease, with the vast majority of lethal bites inflicted by front-fanged snakes from the viperid and elapid groups.
Dominique Koua +6 more
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Snakes of the Philodryadini tribe are included in the Dipsadidae family, which is a diverse group of rear-fanged snakes widespread in different ecological conditions, including habitats and diet. However, little is known about the composition and effects
Emilly Campos Tioyama +9 more
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C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera
Systemic complement activation drives a plethora of pathological conditions, but its role in snake envenoming remains obscure. Here, we explored complement’s contribution to the physiopathogenesis of Naja annulifera envenomation.
Felipe Silva de França +6 more
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Colubrid Venom Composition: An -Omics Perspective
Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes, which actually represent a relatively small proportion of extant species of advanced snakes ...
Inácio L. M. Junqueira-de-Azevedo +3 more
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