Results 31 to 40 of about 112,374 (150)

Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis. [PDF]

PLoS Neglected Tropical Diseases, 2016
The time-course of the pathological effects induced by the venom of the snake Bothrops asper in muscle tissue was investigated by a combination of histology, proteomic analysis of exudates collected in the vicinity of damaged muscle, and immunodetection ...
Cristina Herrera, Jéssica Kele A Macêdo, Andrés Feoli, Teresa Escalante, Alexandra Rucavado, José María Gutiérrez, Jay W Fox   +6 more
doaj   +1 more source

Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities

Frontiers in Ecology and Evolution, 2019
Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected.
Cassandra M. Modahl, Stephen P. Mackessy
doaj   +1 more source

Inflammation and Oxidative Stress in Snakebite Envenomation: A Brief Descriptive Review and Clinical Implications

Toxins, 2022
Snakebite envenoming is a pathological condition which may occur in response to the injection of venom. Snake venoms contain a complex mixture of biologically active molecules which are responsible for a broad spectrum of clinical manifestations, ranging
Dabor Resiere, Hossein Mehdaoui, Remi Neviere   +2 more
doaj   +1 more source

Free Energy Calculations on Snake Venom Metalloproteinase BaP1 [PDF]

Chemical Biology & Drug Design, 2012
BaP1 is a snake venom metalloproteinase from the venom of Bothrops asper, showing high structural homology with the catalytic domain of human adamalysins and matrix metalloproteinases. It induces the release of cytokines, like interleukin‐1 and tumor necrosis factor alpha.
Lingott, T., Merfort, I., Steinbrecher, T.   +2 more
openaire   +3 more sources

Crotalid Snake Venom Subproteomes Unraveled by the Antiophidic Protein DM43

, 2016
Snake venoms are mixtures of proteins and peptides with different biological activities, many of which are very toxic. Several animals, including the opossum Didelphis aurita, are resistant to snake venoms due to the presence of neutralizing factors in ...
Surza L. G. Rocha (2377714), Ana G. C. Neves-Ferreira (2333770), Richard H. Valente (158989), Gilberto B. Domont (1302003), Alex Chapeaurouge (2210758), Monique R. O. Trugilho (2118361), Ileana R. León (1903462), Jonas Perales (158987)   +7 more
core   +5 more sources

49. The Origin and Evolution of Metalloproteinases in the Venom of Snakes

Toxicon, 2012
Background: Snake venom metalloproteinases (SVMPs) are a pathologically-important, often major, toxin component of snake venoms, particularly in the venoms of viperid snakes. The SVMPs are members of the large multi-locus adamalysin gene family alongside ADAM (a disintegrin and metalloproteinase) and ADAMTS (ADAM with thrombospondin motifs) proteins ...
Casewell, N.R., Wüster, W., Wagstaff, S.C., Renjifo, C., Richardson, M.K., Vonk, F.J., Harrison, R.A.   +6 more
openaire   +2 more sources

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system

Heliyon
Snake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong, Cai-E Wang, Ya-Nan Li, Qi-Yun Zhang, Qian-Yun Sun   +4 more
doaj   +1 more source

The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus)

BMC Genomics, 2012
Background Snake venoms have significant impacts on human populations through the morbidity and mortality associated with snakebites and as sources of drugs, drug leads, and physiological research tools.
Rokyta Darin R, Lemmon Alan R, Margres Mark J, Aronow Karalyn   +3 more
doaj   +1 more source

Effect of Vipera ammodytes ammodytes Snake Venom on the Human Cytokine Network

Toxins, 2018
Local inflammation is a well-known symptom of envenomation by snakes of the family Viperidae, attributed primarily to the phospholipase A2s, metalloproteinases and L-amino acid oxidases contained in their venom.
Francisc Boda, Krisztina Banfai, Kitti Garai, Augustin Curticapean, Lavinia Berta, Emese Sipos, Krisztian Kvell   +6 more
doaj   +1 more source

The effect of a serum containing acetyl hexapeptide‐8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies

International Journal of Cosmetic Science, EarlyView.
The novel serum demonstrates significant anti‐skin aging effects, effectively improving static and dynamic wrinkles and skin texture. Therefore, this formulation holds promise as a safe and effective product in the field of anti‐wrinkle skincare products.
Mingjie Zhu, Xiaofeng He, Zailing Zhu, Stephen Lynch, Hequn Wang, Xiaoyin Zhou, Yidong Tu, Andrew Steel, Kung Chi Hsu, Yueqing Niu, Anna Cho, Mutsue Hashimoto, Xi Yan, Maggie Su, Wenna Wang   +14 more
wiley   +1 more source