Results 21 to 30 of about 112,374 (150)

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ, Rucavado Romero, Alexandra, Rucavado, A, Cristina Herrera (576490), Jéssica Kele A. Macêdo (729670), Morazan, D, Diego Morazán (729669), Mathieu-Benoit Voisin (729668), Escalante, Teresa, Libia Sanz, Mathieu-Benoit Voisin, Alexandra Rucavado (32147), Herrera, C, Macêdo, Jéssica Kele A., Jéssica Kele A Macêdo, Teresa Escalante, Calvete Chornet, Juan José, Nourshargh, S, Diego Morazán, Cristina Herrera, Voisin, Mathieu-Benoit, Voisin, M-B, Maria Gutierrez, J, Rucavado, Alexandra, Jay W Fox, José María Gutiérrez, Alexandra Rucavado, Macedo, JKA, Libia Sanz (144843), Juan J. Calvete (144840), Sanz, L, Juan J Calvete, Sussan Nourshargh (157725), Sanz, Libia, Morazán, Diego, Nourshargh, Sussan, Jay W. Fox (164576), Escalante, T, Teresa Escalante (337914), Herrera, Cristina, Calvete, Juan J., Sussan Nourshargh, José María Gutiérrez (62868), Escalante Muñoz, Teresa, Herrera Arias, Cristina, Fox, JW, Fox, Jay W., Gutiérrez, José María   +47 more
core   +1 more source

Snake venom metalloproteinases and disintegrins: interactions with cells [PDF]

Brazilian Journal of Medical and Biological Research, 1998
Metalloproteinases and disintegrins are important components of most viperid and crotalid venoms. Large metalloproteinases referred to as MDC enzymes are composed of an N-terminal Metalloproteinase domain, a Disintegrin-like domain and a Cys-rich C-terminus.
Kamiguti, A.S., Zuzel, M., Theakston, R.D.G.   +2 more
openaire   +5 more sources

Pharmacological aspects of Vipera xantina palestinae venom [PDF]

, 2011
In Israel, Vipera xantina palestinae (V.x.p.) is the most common venomous snake, accounting for several hundred cases of envenomation in humans and domestic animals every year, with a mortality rate of 0.5 to 2%.
Katzhendler, Jeoshua, Franziska T. Arlinghaus, Jeoshua Katzhendler, Cezary Marcinkiewicz, Philip Lazarovici, Arlinghaus, Franziska T., Johannes A. Eble, Lazarovici, Philip, Momic, Tatjana, Eble, Johannes A., Hadar Arien-Zakay, Marcinkiewicz, Cezary, Tatjana Momic, Arien-Zakay, Hadar, Arlinghaus, Franziska Therese   +14 more
core   +1 more source

Snake bite in South Asia: a review [PDF]

, 2010
Snake bite is one of the most neglected public health issues in poor rural communities living in the tropics. Because of serious misreporting, the true worldwide burden of snake bite is not known.
Alirol, Emilie, Sharma Sanjib Kumar, Kuch, Ulrich, Sharma, Sanjib Kumar, Sanjib Kumar Sharma, Alirol Emilie, Bawaskar, Himmatrao Saluba, Emilie Alirol, François Chappuis, Kuch Ulrich, Ulrich Kuch, Himmatrao Saluba Bawaskar, Chappuis, François, Chappuis François, Bawaskar Himmatrao Saluba   +14 more
core   +2 more sources

Comprehensive Snake Venomics of the Okinawa Habu Pit Viper, Protobothrops flavoviridis, by Complementary Mass Spectrometry-Guided Approaches

Molecules, 2018
The Asian world is home to a multitude of venomous and dangerous snakes, which are used to induce various medical effects in the preparation of traditional snake tinctures and alcoholics, like the Japanese snake wine, named Habushu.
Maik Damm, Benjamin-Florian Hempel, Ayse Nalbantsoy, Roderich D. Süssmuth   +3 more
doaj   +1 more source

De Novo Venom-Gland Transcriptomics of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia—Next-Generation Sequencing, Functional Annotation and Toxinological Correlation

Toxins, 2021
Envenomation resulted from sea snake bite is a highly lethal health hazard in Southeast Asia. Although commonly caused by sea snakes of Hydrophiinae, each species is evolutionarily distinct and thus, unveiling the toxin gene diversity within individual ...
Choo Hock Tan, Kae Yi Tan
doaj   +1 more source

Natural Inhibitors of Snake Venom Metalloproteinases

Australian Journal of Chemistry, 2020
Snakebites are a hazard in the tropical world. Although antivenom therapy is effective, it is beset with inherent drawbacks. A better understanding of the major components of snake venoms and their neutralisation will help in improving snakebite treatment.
Narumi Aoki-Shioi, Cho Yeow Koh, R. Manjunatha Kini   +2 more
openaire   +2 more sources

Inhibition of bacterial biofilms by the snake venom proteome

Biotechnology Reports, 2023
Snake venoms possess a range of pharmacological and toxicological activities. Here we evaluated the antibacterial and anti-biofilm activity against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MSSA and MRSA) of venoms from the
Neyaz A. Khan, Fernanda G. Amorim, John P. Dunbar, Dayle Leonard, Damien Redureau, Loïc Quinton, Michel M. Dugon, Aoife Boyd   +7 more
doaj   +1 more source

Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms

Acta Pharmaceutica Sinica B, 2020
Repurposing small molecule drugs and drug candidates is considered as a promising approach to revolutionise the treatment of snakebite envenoming. In this study, we investigated the inhibiting effects of the small molecules varespladib (nonspecific ...
Chunfang Xie, Julien Slagboom, Laura-Oana Albulescu, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Jeroen Kool   +6 more
doaj   +1 more source

Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution. [PDF]

PLoS Neglected Tropical Diseases, 2016
Envenomation of humans by snakes is a complex and continuously evolving medical emergency, and treatment is made that much more difficult by the diverse biochemical composition of many venoms.
Cassandra M Modahl, Stephen P Mackessy
doaj   +1 more source