Results 21 to 30 of about 32,635 (169)
Toxins, 2023 In Southeast Asia, the Malayan Pit Viper (Calloselasma rhodostoma) is a venomous snake species of medical importance and bioprospecting potential. To unveil the diversity of its toxin genes, this study de novo assembled and analyzed the venom gland ...
Choo Hock Tan +4 more
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A transcriptomic view of the proteome variability of newborn and adult Bothrops jararaca snake venoms. [PDF]
PLoS Neglected Tropical Diseases, 2012 BACKGROUND: Snake bite is a neglected public health problem in communities in rural areas of several countries. Bothrops jararaca causes many snake bites in Brazil and previous studies have demonstrated that the pharmacological activities displayed by ...
André Zelanis +6 more
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Structure and Function of Snake Venom Metalloproteinase Family [PDF]
Journal of Protein Chemistry, 1992 Venoms of snakes belonging to families Viperidae (viper) and Crotalidae (pit viper) produce striking local effects, consisting of hemorrhage, necrosis, and edema, and often induce marked alterations of blood coagulation system as well (Iwanaga and Suzuki, 1979). Among these pathological effects, hemorrhage is a most common occurrence in a victim bitten
Sadaaki Iwanaga, Hiroyuki Takeya
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Biochemistry and toxicology of proteins and peptides purified from the venom of Vipera berus berus
Toxicon: X, 2022 The isolation and characterization of individual snake venom components is important for a deeper understanding of the pathophysiology of envenomation and for improving the therapeutic procedures of patients. It also opens possibilities for the discovery
Jüri Siigur, PhD, Ene Siigur, PhD
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Snake venom metalloproteinases and disintegrins: interactions with cells [PDF]
Brazilian Journal of Medical and Biological Research, 1998 Metalloproteinases and disintegrins are important components of most viperid and crotalid venoms. Large metalloproteinases referred to as MDC enzymes are composed of an N-terminal Metalloproteinase domain, a Disintegrin-like domain and a Cys-rich C-terminus.
Kamiguti, A.S. +2 more
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Toxins, 2017 Rhabdophis lateralis, a colubrid snake distributed throughout the continent of Asia, has recently undergone taxonomic revisions. Previously, Rhabdophis lateralis was classified as a subspecies of R. tigrinus (Yamakagashi) until 2012, when several genetic
Yumiko Komori +6 more
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Biomedicines, 2020 Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number of limitations associated with their efficacy, safety and affordability for use in tropical snakebite ...
Chunfang Xie +6 more
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Mediators of Inflammation, 2000 The venom of the snake Bothrops asper, the most important poisonous snake in Central America, evokes an inflammatory response, the mechanisms of which are not well characterized. The objectives of this study were to investigate whether B. asper venom and
Sandra H. P. Farsky +6 more
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Toxins, 2020 The karst viper (Vipera ursinii ssp.) favours high-mountain dry grasslands in southern and south-eastern Croatia. It is medically less important than other Vipera species, because of its remote habitat and the very small amount of venom that it injects ...
Maja Lang Balija +6 more
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Free Energy Calculations on Snake Venom Metalloproteinase BaP1 [PDF]
Chemical Biology & Drug Design, 2012 BaP1 is a snake venom metalloproteinase from the venom of Bothrops asper, showing high structural homology with the catalytic domain of human adamalysins and matrix metalloproteinases. It induces the release of cytokines, like interleukin‐1 and tumor necrosis factor alpha.
Lingott, T. +2 more
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