Results 11 to 20 of about 127,375 (121)
Inflammatory effects of snake venom metalloproteinases [PDF]
Memorias do Instituto Oswaldo Cruz, 2005 Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They are relevant in the pathophysiology of envenomation, being responsible for local and systemic hemorrhage frequently observed in the victims.
Catarina de Fátima Pereira Teixeira +3 more
doaj +4 more sources
Bothrops asper snake venom and its metalloproteinase BaP–1 activate the complement system. Role in leucocyte recruitment [PDF]
Mediators of Inflammation, 2000 The venom of the snake Bothrops asper, the most important poisonous snake in Central America, evokes an inflammatory response, the mechanisms of which are not well characterized. The objectives of this study were to investigate whether B. asper venom and
Sandra H. P. Farsky +6 more
doaj +2 more sources
Data for a direct fibrinolytic metalloproteinase, barnettlysin-I from Bothrops barnetti (barnett,s pitviper) snake venom with anti-thrombotic effect [PDF]
Data in Brief, 2016 Initial association of platelets after vascular injury is mediated by glycoprotein (GP)Ib-IX-V binding to von Willebrand factor (vWf) immobilized on exposed collagens and eventually leads to thrombus formation.
Eladio Flores Sanchez +8 more
doaj +2 more sources
Purified zymogens reveal mechanisms of snake venom metalloproteinase auto-activation
eLifeSnake venoms contain diverse mixtures of toxins that evolved to incapacitate prey, but in humans, they cause extensive pathology following snakebite envenomation. In viper venom, some of the most potent toxins are the haemorrhagic and coagulopathic snake
Sophie Hall +17 more
doaj +5 more sources
Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]
, 2015 20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ +47 more
core +1 more source
, 2021 Elapid snake venom is highly valuable and also a source of medically important peptides. The venom of Naja nigricollis is unique among elapids in that it contains mainly cytotoxins, but also with other components.
Kurfi, Binta G. +2 more
core +1 more source
Pharmacological aspects of Vipera xantina palestinae venom [PDF]
, 2011 In Israel, Vipera xantina palestinae (V.x.p.) is the most common venomous snake, accounting for several hundred cases of envenomation in humans and domestic animals every year, with a mortality rate of 0.5 to 2%.
Katzhendler, Jeoshua +14 more
core +1 more source
Snake bite in South Asia: a review [PDF]
, 2010 Snake bite is one of the most neglected public health issues in poor rural communities living in the tropics. Because of serious misreporting, the true worldwide burden of snake bite is not known.
Alirol, Emilie +14 more
core +2 more sources
Biomedicines, 2020 Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number of limitations associated with their efficacy, safety and affordability for use in tropical snakebite ...
Chunfang Xie +6 more
doaj +1 more source
Toxins, 2017 Rhabdophis lateralis, a colubrid snake distributed throughout the continent of Asia, has recently undergone taxonomic revisions. Previously, Rhabdophis lateralis was classified as a subspecies of R. tigrinus (Yamakagashi) until 2012, when several genetic
Yumiko Komori +6 more
doaj +1 more source