Results 11 to 20 of about 32,635 (169)

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]

Biochem Res Int
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR, Pinos Tamayo EA, Moreira Dos Santos D, Kim B, Almeida JR, Ribeiro RIMA.   +5 more
europepmc   +2 more sources

Snake Venom Metalloproteinases [PDF]

Acta Medica Marisiensis, 2016
Abstract As more data are generated from proteome and transcriptome analysis revealing that metalloproteinases represent most of the Viperid and Colubrid venom components authors decided to describe in a short review a classification and some of the multiple activities of snake venom metalloproteinases.
Teresa Escalante, Alexandra Rucavado, María Gutiérrez, null José   +3 more
  +6 more sources

Venomics of the Arabian saw-scaled viper (Echis coloratus) through transcriptome-guided proteomics and in vitro functional profiling. [PDF]

PLoS Neglected Tropical Diseases
The Arabian saw-scaled viper (Echis coloratus) is among the snakes of highest medical relevance in the Middle East and North Africa. However, to date, its venom has been investigated in a very limited number of studies, and much remains unknown regarding
Ignazio Avella, Lennart Schulte, Maik Damm, Lilien Uhrig, Alfredo Cabrera-Orefice, Johanna Eichberg, Kornelia Hardes, Sabine Hurka, Thomas Lindner, Andreas Vilcinskas, Tim Lüddecke   +10 more
doaj   +2 more sources

Qualitative Analysis of Proteins in Two Snake Venoms, Gloydius Blomhoffii and Agkistrodon Acutus

Journal of Pharmacopuncture, 2022
Objectives: Snake venom is a complex mixture of various pharmacologically active substances, such as small proteins, peptides, and organic and mineral components.
Su-Jeong Ha, Yeo-Ok Choi, Eun-Bin Kwag, Soo-Dam Kim, Hwa-seung Yoo, In-Cheol Kang, So-Jung Park   +6 more
doaj   +1 more source

Antiprotozoal Effect of Snake Venoms and Their Fractions: A Systematic Review

Pathogens, 2021
Background: Protozoal infection is a lingering public health issue of great concern, despite efforts to produce drugs and vaccines against it. Recent breakthrough research has discovered alternative antiprotozoal agents encompassing the use of snake ...
Zainab U. Abdullahi, Salihu S. Musa, Daihai He, Umar M. Bello   +3 more
doaj   +1 more source

Snake Venom Metalloproteinases [PDF]

, 2017
UCR::Vicerrectoría de Docencia::Salud::Facultad de ...
José María Gutiérrez, Jay Fox
openaire   +3 more sources

Venom-gland transcriptomics of the Malayan pit viper (Calloselasma rhodostoma) for identification, classification, and characterization of venom proteins

Heliyon, 2023
The Malayan pit viper (Calloselasma rhodostoma) is a hemotoxic snake widely found in Southeast Asia and is responsible for the majority of poisoning cases in this region, including Thailand. However, a comprehensive knowledge of the venom protein profile
Poom Adisakwattana, Lawan Chanhome, Narongsak Chaiyabutr, Orawan Phuphisut, Onrapak Reamtong, Charin Thawornkuno   +5 more
doaj   +1 more source

Structure-Function Relationship of the Disintegrin Family: Sequence Signature and Integrin Interaction

Frontiers in Molecular Biosciences, 2021
Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors involved in cell-cell and cell-matrix interaction that are widely studied as therapeutic ...
Ariana A. Vasconcelos, Ariana A. Vasconcelos, Jorge C. Estrada, Victor David, Luciana S. Wermelinger, Fabio C. L. Almeida, Fabio C. L. Almeida, Russolina B. Zingali   +7 more
doaj   +1 more source

P-I snake venom metalloproteinase is able to activate the complement system by direct cleavage of central components of the cascade. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Snake Venom Metalloproteinases (SVMPs) are amongst the key enzymes that contribute to the high toxicity of snake venom. We have recently shown that snake venoms from the Bothrops genus activate the Complement system (C) by promoting direct ...
Giselle Pidde-Queiroz, Fábio Carlos Magnoli, Fernanda C V Portaro, Solange M T Serrano, Aline Soriano Lopes, Adriana Franco Paes Leme, Carmen W van den Berg, Denise V Tambourgi   +7 more
doaj   +1 more source

Venom Variation of Neonate and Adult Chinese Cobras in Captivity Concerning Their Foraging Strategies

Toxins, 2022
The venom and transcriptome profile of the captive Chinese cobra (Naja atra) is not characterized  until now. Here, LC-MS/MS and illumine technology were used to unveil the venom and trascriptome of neonates and adults N. atra specimens.
Xuekui Nie, Qianzi Chen, Chen Wang, Wangxiang Huang, Ren Lai, Qiumin Lu, Qiyi He, Xiaodong Yu   +7 more
doaj   +1 more source