Results 41 to 50 of about 14,839 (236)
The electronic structure and dipole moment of charybdotoxin, a scorpion venom peptide with K+ channel blocking activity [PDF]
Computational and Theoretical Chemistry 963 (2011) 384-393, 2010 The electronic structure of charybdotoxin (ChTX), a scorpion venom peptide that is known to act as a potassium channel blocker, is investigated with the aid of quantum mechanical calculations. The dipole moment vector (145 D) of ChTX can be stirred by the full length KcsA potassium channel's macrodipole (403 D) thereby assuming the proper orientation ...
arxiv +1 more source
Toxins, 2014 Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar +10 more
doaj +1 more source
Looptree, Fennec, and Snake of ICRT [PDF]
arXiv, 2022 We introduce a new theory of plane $\mathbb R$-tree, to define plane ICRT (inhomogeneous continuum random tree), and its looptree, fennec (a Gaussian free field on the looptree), and snake. We prove that a.s. the looptree is compact, and that a.s. the fennec and snake are continuous.
arxiv
Snake Venomics Display: An online toolbox for visualization of snake venomics data [PDF]
Toxicon, 2018 With the introduction of powerful mass spectrometry equipment into the field of snake venom proteomics, a large body of venomics data is accumulating. To allow for better comparison between venom compositions from different snake species and to provide an online database containing this data, we devised the Snake Venomics Display toolbox for ...
Søren H. Dam +4 more
openaire +4 more sources
Toxins, 2022 Snake envenoming causes rapid systemic and local effects that often result in fatal or long-term disability outcomes. It seems likely that acute phase and inflammatory responses contribute to these haemorrhagic, coagulopathic, neurotoxic, nephrotoxic and
Jaffer Alsolaiss +4 more
doaj +1 more source
Frontiers in Ecology and Evolution, 2019 Animal venoms have evolved over millions of years for prey capture and defense from predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides and proteins that induce harmful inflammatory and neurotoxic effects ...
Camila R. Ferraz +7 more
doaj +1 more source
Journal of Venomous Animals and Toxins including Tropical Diseases, 2009 Bothrops snake venoms have been proved toxic to a variety of cell types, in both in vivo and in vitro models. Studies on the pharmacological actions of Bothrops venoms from Argentina are relatively scarce and the direct action of the crude venoms has not
S Bustillo +5 more
doaj +1 more source
eLife, 2023 For decades, studies of snake venoms focused on the venom-ome-specific toxins (VSTs). VSTs are dominant soluble proteins believed to contribute to the main venomous effects and emerged into gene clusters for fast adaptation and diversification of snake ...
Cheng-Tsung Pan +6 more
doaj +1 more source
Biology, 2022 Hybridization is defined as the interbreeding of individuals from two populations distinguishable by one or more heritable characteristics. Snake hybridization represents an interesting opportunity to analyze variability and how genetics affect the venom
Octavio Roldán-Padrón +8 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2020 Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year.
Julien Slagboom +7 more
doaj +1 more source