Results 1 to 10 of about 73,344 (342)

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitro. [PDF]

PLoS ONE, 2008
Translocation of the facilitative glucose transporter GLUT4 from an intracellular store to the plasma membrane is responsible for the increased rate of glucose transport into fat and muscle cells in response to insulin. This represents a specialised form
Fiona M Brandie, Veronica Aran, Avani Verma, James A McNew, Nia J Bryant, Gwyn W Gould   +5 more
doaj   +25 more sources

Conformational change of Syntaxin-3b in regulating SNARE complex assembly in the ribbon synapses [PDF]

Scientific Reports, 2022
Neurotransmitter release of synaptic vesicles relies on the assembly of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, consisting of syntaxin and SNAP-25 on the plasma membrane and synaptobrevin on the synaptic
Claire Gething, Joshua Ferrar, Bishal Misra, Giovanni Howells, Alexa L. Andrzejewski, Mark E. Bowen, Ucheor B. Choi   +6 more
doaj   +2 more sources

Rapamycin Affects the Hippocampal SNARE Complex to Alleviate Cognitive Dysfunction Induced by Surgery in Aged Rats [PDF]

Brain Sciences, 2023
Delayed neurocognitive recovery (dNCR) is a common complication that occurs post-surgery, especially in elderly individuals. The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex plays an essential role in various ...
Ning Kang, Xiaoguang Han, Zhengqian Li, Taotao Liu, Xinning Mi, Yue Li, Xiangyang Guo, Dengyang Han, Ning Yang   +8 more
doaj   +2 more sources

Ca2+-dependent release of synaptotagmin-1 from the SNARE complex on phosphatidylinositol 4,5-bisphosphate-containing membranes [PDF]

eLife, 2020
The Ca2+ sensor synaptotagmin-1 and the SNARE complex cooperate to trigger neurotransmitter release. Structural studies elucidated three distinct synaptotagmin-1-SNARE complex binding modes involving ‘polybasic’, ‘primary’ and ‘tripartite’ interfaces of ...
Rashmi Voleti, Klaudia Jaczynska, Josep Rizo   +2 more
doaj   +2 more sources

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex. [PDF]

Proc Natl Acad Sci U S A
Dash BK, Urano Y, Mita Y, Ashida Y, Hirose R, Noguchi N.   +5 more
europepmc   +3 more sources

Structural principles of SNARE complex recognition by the AAA+ protein NSF [PDF]

eLife, 2018
The recycling of SNARE proteins following complex formation and membrane fusion is an essential process in eukaryotic trafficking. A highly conserved AAA+ protein, NSF (N-ethylmaleimide sensitive factor) and an adaptor protein, SNAP (soluble NSF ...
K Ian White, Minglei Zhao, Ucheor B Choi, Richard A Pfuetzner, Axel T Brunger   +4 more
doaj   +2 more sources

SNAP to attention: A SNARE complex regulates neuronal progenitor polarity. [PDF]

J Cell Biol, 2021
Tarabykin V.
europepmc   +3 more sources

GPNMB disrupts SNARE complex assembly to maintain bacterial proliferation within macrophages. [PDF]

Cell Mol Immunol
Yan Z, Han J, Mi Z, Wang Z, Fu Y, Wang C, Dang N, Liu H, Zhang F.   +8 more
europepmc   +3 more sources

Tyramine synthesis, vesicular packaging, and the SNARE complex function coordinately in astrocytes to regulate Drosophila alcohol sedation. [PDF]

Addict Biol, 2021
Lee KM, Talikoti A, Shelton K, Grotewiel M.   +3 more
europepmc   +3 more sources

Structural Dynamics of SNARE Complex Assembly in the Ribbon Synapses Observed by smFRET. [PDF]

Methods Mol Biol
Andrzejewski AL, Ferrar J, Kratzer-Charron M, Bowen ME, Choi UB.   +4 more
europepmc   +3 more sources