Results 141 to 150 of about 12,300 (184)

Amyloid formation of alternatively spliced variants of α-synuclein. [PDF]

Protein Sci
SanGiovanni DQ, McGlinchey RP, Lee JC.
europepmc   +1 more source

Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy. [PDF]

Front Immunol
Liang Q, Wang J, Nong Q, Tao S, Fang D.
europepmc   +1 more source

Differential methylation of <i>SNCA</i> and <i>MAPT</i> genes associated with Parkinson's disease in Mexican Mestizos. [PDF]

Front Aging Neurosci
Miranda-Morales EG, Ramos-Rosales DF, Salas-Leal AC, Salas-Pacheco SM, Castellanos-Juárez FX, Méndez-Hernández EM, La Llave-León O, Peñaherrera MS, Quiñones-Canales G, Arias-Carrión O, Sandoval-Carrillo AA, Salas-Pacheco JM.   +11 more
europepmc   +1 more source

Molecular mechanisms of α-syn abnormal phase separation in cognitive impairment induced by chronic intermittent hypoxia and the neuroprotective effects of Danshensu methyl ester. [PDF]

Mol Med
Li J, Zhang N, Zhang Z, Fu J, Ren W, Sun Y, Song S, Liu X, Liu J, Wang J, Sun Y, Zhang K, Guo R, Lv C, Pan L, Qu G, Han F, Yu Y.   +17 more
europepmc   +1 more source

Gabapentinoids promote striatal dopamine release and rescue multiple deficits of a mouse model of early Parkinson’s

Brimblecombe KR, Harris AL, Bengoa-Vergniory N, O’Connor B, Duquenoy L, Anand R, Lopes EF, Roberts BM, Burgeno L, Walton ME, Cragg SJ.   +10 more
europepmc   +1 more source

A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease [PDF]

Movement Disorders, 2021
ABSTRACTBackgroundThe SNCA gene encoding α‐synuclein (αSyn) is the first gene identified to cause autosomal‐dominant Parkinsonʼs disease (PD).ObjectiveWe report the identification of a novel heterozygous A30G mutation of the SNCA gene in familial PD and describe clinical features of affected patients, genetic findings, and functional consequences ...
Hui Liu, Christos Koros, Claudia Schulte
exaly   +6 more sources

Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation [PDF]

Molecular Neurodegeneration, 2015
We and others have described the neurodegenerative disorder caused by G51D SNCA mutation which shares characteristics of Parkinson's disease (PD) and multiple system atrophy (MSA). The objective of this investigation was to extend the description of the clinical and neuropathological hallmarks of G51D mutant SNCA-associated disease by the study of two ...
Aoife P Kiely, Helen Ling, Christos Proukakis   +2 more
exaly   +9 more sources