Results 121 to 130 of about 15,713 (203)

Lipid Challenge Reveals Amplified Apolipoprotein Responses with Preserved Temporal Pattern in Polyendocrine Metabolic Ovarian Syndrome: An Exploratory Study. [PDF]

Int J Mol Sci
Rajab E, Moin ASM, Nandakumar M, Sathyapalan T, Butler AE, Atkin SL.   +5 more
europepmc   +1 more source

PRKN/parkin-mediated control of SNCA (synuclein alpha) and chaperone-mediated autophagy are defective in cellular, mice models and Parkinson disease-affected brains. [PDF]

Autophagy
Ramos Dos Santos L, Duplan E, Debord J, Fremont G, Minniti J, Lauritzen I, Mutez E, Leghay C, Chartier-Harlin MC, Checler F, Alves da Costa C.   +10 more
europepmc   +1 more source

RNA Splicing Dysregulation in Parkinson's Disease. [PDF]

Genes (Basel)
Bruno MG, Menichetti G, Valentino A, Javaid A, Belpinati F, Ruggiero A, Valenti MT, Paolone G, Cavaliere F, Trabetti E, Romanelli MG, Bombieri C.   +11 more
europepmc   +1 more source

A Multi-Locus and Machine Learning-Based Assessment of SNCA Variants in Alzheimer's Disease. [PDF]

Int J Mol Sci
Segmen H, Yildiz M.
europepmc   +1 more source

NERINE reveals rare variant associations in gene networks across phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease. [PDF]

Cell Genom
Nazeen S, Wang X, Morrow AR, Strom R, Ethier E, Ritter D, Henderson ABH, Afroz J, Cassa CS, Stitziel NO, Gupta RM, Luk KC, Studer L, Khurana V, Sunyaev SR.   +14 more
europepmc   +1 more source

SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies

The authors recently have shown that triplication of the α-synuclein gene (SNCA) can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred.
Johnson J, Eerola J, Hellstrom O, Hardy J, Hernandez DG, Jaros E, Gallardo M, Hague SM, Nussbaum RL, McInerney-Leo A, Morris CM, Hanson M, Evans EW, Ravina B, Singleton AB, Singleton AA, Ryu M, Wilson KE, McKeith IG, Perry RH, Burn DJ, Tienari P, Gibson A, Gwinn-Hardy K, Weiser R   +24 more
core   +1 more source

The APOA1-SNCA Axis as a Molecular Bridge Between CKD and Parkinson's Disease: A Systems Biology Model of Kidney-to-Brain Propagation via Exosomal Pathways. [PDF]

Int J Mol Sci
Billur D, Hanagası HA, Bilgic B, Timirci-Kahraman O.   +3 more
europepmc   +1 more source

ALDH1A1-dopaminergic gene co-expression in human substantia nigra: meta-analysis of disease-associated correlation changes across seven independent Parkinson's disease datasets. [PDF]

Front Aging Neurosci
Harbert DH.
europepmc   +1 more source

Strategies for Optimizing Genetic Mouse Models to Enhance the Understanding of Parkinson's Disease. [PDF]

Biomedicines
Shen Z, Ma L, Mellick GD.
europepmc   +1 more source

Genetic Architecture of Synaptic Failure in Dementia with Lewy Bodies: From α-Synuclein Proteoforms to GBA1-Mediated Plasticity Deficits. [PDF]

Genes (Basel)
Bougea A.
europepmc   +1 more source