Results 111 to 120 of about 15,713 (203)

SNCA-targeted transcriptional repression therapy alleviates pathological and behavioral perturbations in a Parkinson's disease mouse model. [PDF]

Neurotherapeutics
O'Donovan B, Rittiner J, Upadhya S, Hodgson D, Kantor B, Chiba-Falek O.   +5 more
europepmc   +1 more source

Independent and joint effects of the MAPT and SNCA genes in Parkinson disease

, 2011
OBJECTIVE: We studied the independent and joint effects of the genes encoding alpha-synuclein (SNCA) and microtubule-associated protein tau (MAPT) in Parkinson disease (PD) as part of a large meta-analysis of individual data from case-control studies ...
Chartier-Harlin, M. C., Stefanis, L., Valente, E. M., Jasinska-Myga, B., Mellick, G. D., Moisan, F., Ferrarese, C., Vilarino-Guell, C., Lambert, J. C., Xiromerisiou, G., van de Loo, S., Brighina, L., Lohmann, K., Sharma, M., Elbaz, A., Ferraris, A., Farrer, M. J., Gibson, J. M., Klein, C., Destee, A., Quattrone, A., Hadjigeorgiou, G. M., Maraganore, D. M., Nilsson, C., Aasly, J. O., Opala, G., Soto-Ortolaza, A. I., Ross, O. A., Wszolek, Z. K., Annesi, G., Mutez, E., Kruger, R., Uitti, R. J., Wirdefeldt, K., Loriot, M. A., Puschmann, A., Silburn, P. A., Ioannidis, J. P., Gispert, S., Bozi, M., Lynch, T.   +40 more
core  

α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease. [PDF]

Nat Commun
Lam CL, Gatford NJF, Aragón-González A, Tanudjojo B, Sahoo A, Castle AR, Agarwal D, Jainarayanan A, Hester SS, Sen N, Benesch JLP, Fischer R, Sims D, Tofaris GK.   +13 more
europepmc   +1 more source

Cholesterol dysregulation in APOE4 astrocytes promotes α-synuclein pathology in miBrains. [PDF]

Cell Stem Cell
Mesentier-Louro LA, Goldman C, Gaese S, Buonfiglioli A, Kyriakis D, Harlock A, Ndayisaba A, Sartori ER, Uchitelev A, Fullard JF, Hennigan E, Lee D, Schuldt BR, Rooklin RB, Barra J, Bravo-Cordero JJ, Roussos P, Khurana V, Blanchard JW.   +18 more
europepmc   +1 more source

Calcineurin; α-synuclein (SNCA) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Neuronal titration of Snca via enhancer disruption mitigates disease onset in a Parkinson's disease mouse model. [PDF]

Brain
Boyd RJ, Kho AR, McClymont SA, Loftus SK, Ko HS, McCallion AS.   +5 more
europepmc   +1 more source

α-Synuclein burden amplification in Parkinson's disease: a unified genetic, molecular, and cellular framework. [PDF]

Front Neurol
Noda S, Hattori N.
europepmc   +1 more source

Colorectal Cancer Liver Metastasis-Associated Ferroptosis-Related Genes Modulate Lipid Peroxidation in Colorectal Cancer Cells. [PDF]

Mol Carcinog
Ge Z, Guo W, Li J, Wang Y, Wang K.
europepmc   +1 more source

Investigation of correlation between cholesterol intake, apolipoprotein B and Parkinson's disease related genes in guinea pigs feeding a high-fat diet containing cholesterol. [PDF]

PLoS One
Kacamak P, Elmas C, Tokcaer Bora HA, Babaoglu Aydas SS.   +3 more
europepmc   +1 more source

Altered light-dark phase-dependent behavioral responses and suprachiasmatic nucleus pathology in an α-synuclein rat model of Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Weber H, Statz M, Casadei N, Riess O, Richter F, Hermann W, Storch A, Fauser M.   +7 more
europepmc   +1 more source