Results 81 to 90 of about 2,855 (178)

The Arabidopsis NST3/SND1 promoter is active in secondary woody tissue in poplar [PDF]

Journal of Wood Science, 2017
Wood biomass is one of the promising future materials for biofuels with no competing food uses. However, the higher cost to produce bioethanol from wood feedstocks is regarded as a priority issue. Genetic engineering techniques have been proposed to enhance the quality and quantity of wood materials to overcome the cost problem.
Naoki Takata, Shingo Sakamoto, Nobutaka Mitsuda, Toru Taniguchi   +3 more
openaire   +1 more source

Arabidopsis NAC domain proteins, VND1 to VND5, are transcriptional regulators of secondary wall biosynthesis in vessels. [PDF]

PLoS ONE, 2014
One of the most prominent features of xylem conducting cells is the deposition of secondary walls. In Arabidopsis, secondary wall biosynthesis in the xylem conducting cells, vessels, has been shown to be regulated by two VASCULAR-RELATED NAC-DOMAIN (VND)
Jianli Zhou, Ruiqin Zhong, Zheng-Hua Ye
doaj   +1 more source

Pathological Roles of Astrocytes in Traumatic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
TBI induces intrinsic astrocytic changes, including reactive astrogliosis, A1 and A2 polarization, ion channels activation, pathological edema, oxidative stress, and metabolic dysregulation. These injury‐responsive astrocytes regulate neuroinflammation and tissue remodeling through dynamic crosstalk with microglia, macrophages, vascular endothelial ...
Di Wu, Yuxiao Ma, Baofeng Wang, Yongtao Zheng, Jie Ren, Qingfang Sun, Liuguan Bian, Yuhao Sun   +7 more
wiley   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, Volume 5, Issue 2, April 2026.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source

Suppression of miR-184 in malignant gliomas upregulates SND1 and promotes tumor aggressiveness [PDF]

Neuro-Oncology, 2014
Malignant glioma is an aggressive cancer requiring new therapeutic targets. MicroRNAs (miRNAs) regulate gene expression post transcriptionally and are implicated in cancer development and progression. Deregulated expressions of several miRNAs, specifically hsa-miR-184, correlate with glioma development.Bioinformatic approaches were used to identify ...
Luni, Emdad, Aleksandar, Janjic, Mohammad A, Alzubi, Bin, Hu, Prasanna K, Santhekadur, Mitchell E, Menezes, Xue-Ning, Shen, Swadesh K, Das, Devanand, Sarkar, Paul B, Fisher   +9 more
openaire   +2 more sources

Figure S1 from Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma

, 2017
Generation and characterization of Alb/SND1 ...
Arun J. Sanyal (8605370), Devanand Sarkar (152580), Rachel G. Mendoza (14925857), Nidhi Jariwala (14925854), Chadia L. Robertson (14919417), Maaged A. Akiel (11454661), Paul B. Fisher (152591), Devaraja Rajasekaran (14919423), Xue-Ning Shen (8699220), Ayesha Siddiq (14919420), Mark A. Subler (14919429), Jolene J. Windle (7470833)   +11 more
core   +1 more source

Multi‐omic profiling defines three distinct molecular subtypes of urothelial carcinoma with implications for precision therapy

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
We developed three UC clusters, applicable for MIBC and NMIBC, which were validated using transcriptomic- and proteomic datasets. Publically available UC cell lines were assigned to the clusters, to have in vitro models representing each cluster. The clusters differ in molecular and biological signatures, with distinct prognostic and therapeutic ...
Nils C. H. van Creij, Piotr Tymoszuk, Florian Handle, Andreas Seeber, Teresa Sellemond, Agnieszka Martowicz, Eva Comperat, Hamed Wafa, Steffen Ormanns, Michael Günther, Walther Parson, Maxim Noeparast, Frédéric R. Santer, José Daniel Subiela, Petros Grivas, Roger Li, Zoran Culig, Renate Pichler   +17 more
wiley   +1 more source

FBXW7 Targets the SPT6‐ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4‐Nitroquinoline N‐Oxide

MedComm, Volume 7, Issue 3, March 2026.
In normal cells, FBXW7 promotes ubiquitylation and degradation of SPT6 and ΔNp63 to keep their pro‐proliferative functions under control. During esophageal tumorigenesis, FBXW7 is inactivated by mutations or deletion, leading to the accumulation of SPT6 and ΔNp63, with ΔNp63 also being up‐regulated by SPT6.
Jiagui Zhang, Lu Yin, Xiahong You, Xiufang Xiong, Yi Sun   +4 more
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

The MTDH–SND1 Complex Is Critical for Mammary Tumor-Initiating Cells [PDF]

Cancer Discovery, 2014
Abstract MTDH is indispensable for tumor-initiating cell function in multiple breast cancer subtypes.
openaire   +1 more source