Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution [PDF]
BACKGROUND: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It is recommended to be taken with milk to enhance its solubility and bioavailability.
Ketan Patel, Pradeep Vavia, Vidur Sarma
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Optimasi Perbandingan Tween 80 Dan Polietilenglikol 400 Pada Formula Self Nanoemulsifying Drug Delivery System (Snedds) Minyak Biji Jinten Hitam [PDF]
Black cumin (Nigella sativa Linn.) seed oil has been known for possessing anticancer activity, with thymoquinone as the active ingredient. Previously reported data show that anticancer activity of thymoquinone is relatively low.
Putranti, W. (Widyasari) +1 more
core +1 more source
Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems [PDF]
The current research work encompasses the development, characterization, and evaluation of self-assembled phospholipidic nano-mixed miceller system (SPNMS) of a poorly soluble BCS Class IV xanthone bioactive, mangiferin (Mgf) functionalized with co ...
Gaspar, Balan Louis +5 more
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Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie +9 more
wiley +1 more source
Jinten hitam (Nigella sativa) mengandung senyawa timokuinon yang berefek sebagai imunostimulan. Ekstrak jinten hitam dikembangkan menjadi SNEDDS (Self-nanoemulsifying Drug Delivery System) karena masalah kelarutan.
Maya Uzia Beandrade
doaj +1 more source
Formulation of gliclazide using self-nano-emulsification technology [PDF]
Self-nano-emulsifying drugs delivery systems present an effective drug delivery system for the formulation of a hydrophobic drug with poor water-solubility.
Abdel-Aziz, Farah +4 more
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Formulation of Insulin Self Nanoemulsifying Drug Delivery System and Its In Vitro-In Vivo Study [PDF]
Particulate delivery system can be used for improving the efficacy of protein and peptide drug. In addition to a polymer-based particulate delivery system, self-nanoemulsifying drug delivery system (SNEDDS), a lipid-based delivery system, is currently ...
Hakim, Lukman +3 more
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Optimasi Tween 80 dan Propilen Glikol dalam Self-Nanoemulsifying Drug Delivery System (SNEDDS) Minyak Atsiri Daun Kemangi (Ocimum basilicum) [PDF]
Basil (Ocimum basilicum) is a plant from Lamiaceae family that has the potential for typhoid fever treatment. Basil essential oil is a hydrophobic compound being difficult to dissolve in the gastrointestinal tract.
Nurahmanto, Dwi +2 more
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Ibuprofen is one of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) class of propionic acid derivatives which has potent anti-inflammatory and antipyretic activity. The solubility of ibuprofen is disadvantageous because it is practically insoluble and
Muhamad Handoyo Sahumena +1 more
doaj +1 more source
Engineering synergistically active and bioavailable cost-effective medicines for neglected tropical diseases; the role of excipients [PDF]
Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world threatening 350 million people mostly in developing countries.
Dea Ayuela, Maria Auxiliadora +2 more
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