Results 81 to 90 of about 3,236 (202)

A Literature Review on Self Nanoemulsifying Drug Delivery System (SNEDDS)

International Journal of Pharmaceutical Sciences Review and Research, 2021
The Lipid-based drug delivery system is extensively reported within the literature for the enhancing drug solubility, permeability, and bioavailability. A considerable majority of novel pharmacologically active constituents produced in recent drug discovery programs are lipophilic and poorly soluble, posing a significant problem for pharmaceutical ...
Saikumar D, Leela Prasanna J
openaire   +1 more source

QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani, Anis Yohana Chaerunisaa, Gofarana Wilar, Iyan Sopyan, Mozhgan Afshari   +4 more
wiley   +1 more source

Development of Guar Gum-Pectin-Based Colon Targeted Solid Self-Nanoemulsifying Drug Delivery System of Xanthohumol

Pharmaceutics, 2022
Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH).
Mahesh Hanmantrao, Sourabh Chaterjee, Rajan Kumar, Sukriti Vishwas, Vancha Harish, Omji Porwal, Mohammed Alrouji, Othman Alomeir, Sharif Alhajlah, Monica Gulati, Gaurav Gupta, Kamal Dua, Sachin Kumar Singh   +12 more
doaj   +1 more source

Karakteristik Nanoemulsi Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) [PDF]

, 2017
Penggunaan ekstrak kulit buah manggis secara langsung dapat menimbulkan ketidaknyamanan dan memiliki ukuran partikel besar sehingga penetrasi dan absorpsinya pada kulit kurang baik, untuk itu dibuat dalam bentuk nanoemulsi dengan Self Nanoemulsifying ...
Astuti, K. W. (K), Lina, N. W. (N), Maharani, T. (T), Sutharini, M. R. (M), Wijayanti, N. P. (N)   +4 more
core  

Optimasi Formula Nanoemulsi Nifedipin Dengan Metode Self-Nanoemulsifying Drug Delivery System (SNEDDS)

Pharmaceutical Journal of Indonesia, 2021
Nifedipin adalah obat golongan calcium channel blocker yang digunakan untuk terapi angina pektoris dan hipertensi. Nifedipin memiliki kelarutan yang rendah dalam air dan bioavailabilitas yang rendah. Berdasarkan penggolongan Biopharmaceutical Classification System (BCS), nifedipin termasuk dalam kelas II.
Zalfa Hibatullah Rahadatul Aisy, Oktavia Eka Puspita, Alvan Febrian Shalas   +2 more
openaire   +2 more sources

Multitarget Anti‐Candida Activity of Thai Plant Extracts and Essential Oils: Inhibiting Biofilm Formation, Denture Adhesion, and Germ Tube Formation

Scientifica, Volume 2025, Issue 1, 2025.
This study aimed to evaluate the efficacy of Thai plant extracts (PEs) and essential oils (EOs) against reference and clinical isolate strains of Candida albicans, focusing on their ability to inhibit biofilm formation, cell adhesion to denture acrylic, and germ tube formation. The minimum biofilm inhibition concentration (MBIC) and the minimum biofilm
Premnapa Sisopa, Supaporn Lamlertthon, Ruchadaporn Kaomongkolgit, Pratthana Chomchalao, Waree Tiyaboonchai, Simone Carradori   +5 more
wiley   +1 more source

Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy

Drug Delivery, 2019
Self-nanoemulsifying drug delivery system (SNEDDS) have been considered as a promising platform for oral delivery of many BCS (biopharmaceutics classification system) class IV drugs, such as docetaxel (DTX).
Weiping Cui, Hanqing Zhao, Chen Wang, Yao Chen, Cong Luo, Shenwu Zhang, Bingjun Sun, Zhonggui He   +7 more
doaj   +1 more source

Development and Evaluation of Simvastatin based Self nano emulsifying drug delivery system for treatment of Alzheimer’s Disease

Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.
Abstract Background Alzheimer’s disease (AD) is one of the leading causes of mortality and morbidity across the globe. Its incidences are increasing at an immense rate due to inadequate patient compliance. Hence there is a requirement for a requisite treatment strategy.
Hardeep  , Narendra Kumar Pandey
wiley   +1 more source

Xanthohumol loaded self‐nano emulsifying drug delivery system: Harnessing neuroprotective effects in Alzheimer’s Disease management [PDF]

Alzheimers Dement
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the impairment of cognitive development and disruption of neurocognitive function. This neuropathological condition is marked by neurodegeneration, loss of neural tissue, and the formation of neurofibrillary tangles and Aβ plaques. Various studies reported the
Bashir B, Singh S, Gulati M, Vishwas S, Dua K.   +4 more
europepmc   +2 more sources

Kaempferol-Phospholipid Complex: Formulation, and Evaluation of Improved Solubility, In Vivo Bioavailability, and Antioxidant Potential of Kaempferol [PDF]

, 2016
The current work describes the formulation and evaluation of a phospholipid complex of kaempferol toenhance the latter’s aqueous solubility, in vitro dissolution rate, in vivo antioxidant and hepatoprotectiveactivities, and oral bioavailability.
Anand, Sridhar, Dave, Vivek S, Patil, Arun T., Pethe, Anil M., Tatode, Amol A., Telange, Darshan R.   +5 more
core   +2 more sources