Results 81 to 90 of about 3,204 (201)

The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

Pharmaceutics, 2023
Reformulating poorly water-soluble drugs as supersaturated lipid-based formulations achieves higher drug loading and potentially improves solubilisation and bioavailability.
Amalie Møller, Hayley B. Schultz, Tahlia R. Meola, Paul Joyce, Anette Müllertz, Clive A. Prestidge   +5 more
doaj   +1 more source

Xanthohumol loaded self‐nano emulsifying drug delivery system: Harnessing neuroprotective effects in Alzheimer’s Disease management [PDF]

Alzheimers Dement
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the impairment of cognitive development and disruption of neurocognitive function. This neuropathological condition is marked by neurodegeneration, loss of neural tissue, and the formation of neurofibrillary tangles and Aβ plaques. Various studies reported the
Bashir B, Singh S, Gulati M, Vishwas S, Dua K.   +4 more
europepmc   +2 more sources

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications

The AAPS Journal
Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs.
Sandrine Tanga, Poornima Ramburrun, Marique Aucamp   +2 more
openaire   +1 more source

A Literature Review on Self Nanoemulsifying Drug Delivery System (SNEDDS)

International Journal of Pharmaceutical Sciences Review and Research, 2021
The Lipid-based drug delivery system is extensively reported within the literature for the enhancing drug solubility, permeability, and bioavailability. A considerable majority of novel pharmacologically active constituents produced in recent drug discovery programs are lipophilic and poorly soluble, posing a significant problem for pharmaceutical ...
Saikumar D, Leela Prasanna J
openaire   +1 more source

Karakteristik Nanoemulsi Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) [PDF]

, 2017
Penggunaan ekstrak kulit buah manggis secara langsung dapat menimbulkan ketidaknyamanan dan memiliki ukuran partikel besar sehingga penetrasi dan absorpsinya pada kulit kurang baik, untuk itu dibuat dalam bentuk nanoemulsi dengan Self Nanoemulsifying ...
Astuti, K. W. (K), Lina, N. W. (N), Maharani, T. (T), Sutharini, M. R. (M), Wijayanti, N. P. (N)   +4 more
core  

Development and Evaluation of Simvastatin based Self nano emulsifying drug delivery system for treatment of Alzheimer’s Disease

Alzheimer's &Dementia, Volume 20, Issue S6, December 2024.
Abstract Background Alzheimer’s disease (AD) is one of the leading causes of mortality and morbidity across the globe. Its incidences are increasing at an immense rate due to inadequate patient compliance. Hence there is a requirement for a requisite treatment strategy.
Hardeep  , Narendra Kumar Pandey
wiley   +1 more source

Development of an Oral Isoliquiritigenin Self-Nano-Emulsifying Drug Delivery System (ILQ-SNEDDS) for Effective Treatment of Eosinophilic Esophagitis Induced by Food Allergy

Pharmaceuticals, 2022
Isoliquiritigenin (ILQ) is a natural flavonoid with various pharmacological activities. In this study, we optimized the preparation method of self-nano-emulsion-loaded ILQ to further improve its bioavailability based on our previous study.
Mingzhuo Cao, Yuan Wang, Heyun Jing, Zeqian Wang, Yijia Meng, Yu Geng, Mingsan Miao, Xiu-Min Li   +7 more
doaj   +1 more source

Optimasi Formula Nanoemulsi Nifedipin Dengan Metode Self-Nanoemulsifying Drug Delivery System (SNEDDS)

Pharmaceutical Journal of Indonesia, 2021
Nifedipin adalah obat golongan calcium channel blocker yang digunakan untuk terapi angina pektoris dan hipertensi. Nifedipin memiliki kelarutan yang rendah dalam air dan bioavailabilitas yang rendah. Berdasarkan penggolongan Biopharmaceutical Classification System (BCS), nifedipin termasuk dalam kelas II.
Zalfa Hibatullah Rahadatul Aisy, Oktavia Eka Puspita, Alvan Febrian Shalas   +2 more
openaire   +2 more sources

Perbandingan Aktivitas Antiinflamasi Ekstrak Etanol Daun Sidaguri (Sida Rhombifolia L.) Dalam Sediaan Selfnanoemulsifying Drug Delivery System (Snedds)dansuspensi Pada Tikus Putih Jantan [PDF]

, 2017
SARI Sidaguri (Sida rhombifolia L.) merupakan tanaman herbal yang telah terbukti memiliki aktivitas antiinflamasi. Penggunaan ekstrak sidaguri pada sediaan oral masih terbatas karena kelarutan ekstrak yang rendah dalam air sehingga berakibat pada ...
Bagiana, I. K. (I), Hapsari, R. D. (Retty), Herlyanti, K. (Kyky)   +2 more
core  

Effects of chrysin loaded self‐nano emulsifying drug delivery system for the treatment of Alzheimer’s disease [PDF]

Alzheimers Dement
Abstract Background Alzheimer’s disease (AD) is a type of degenerative disorder that affects the brain. There are various herbal drugs that have been tested for their effectiveness in treating AD, and chrysin is one of them. Chrysin is a polyphenolic flavonoid that has several neuroprotective effects, including reducing the levels of AChE enzyme ...
Vishwas S, Singh S, Gulati M, Dua K, Kakoty V, Bashir B.   +5 more
europepmc   +2 more sources