Results 31 to 40 of about 1,566,477 (261)
PLoS ONE, 2020 Single nucleotide polymorphisms (SNPs) are highly abundant, amendable to high-throughput genotyping, and useful for a number of breeding and genetics applications in crops.
Karina Y Morales +13 more
semanticscholar +1 more source
BMC Genomics, 2022 Background In preimplantation genetic testing for aneuploidy (PGT-A), appropriate evaluation of mosaic embryos is important because of the adverse implications of transferring embryos with high-level mosaicism or discarding those with low-level mosaicism.
Dongjia Chen +13 more
doaj +1 more source
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia [PDF]
, 2020 In acute lymphoblastic leukaemia, MLPA has been used in research studies to identify clinically relevant copy number abnormality (CNA) profiles. However, in diagnostic settings other techniques are often employed.
Bashton, Matthew +7 more
core +1 more source
Identification of Pyrus single nucleotide polymorphisms (SNPs) and evaluation for genetic mapping in European pear and interspecific Pyrus hybrids. [PDF]
PLoS ONE, 2013 We have used new generation sequencing (NGS) technologies to identify single nucleotide polymorphism (SNP) markers from three European pear (Pyrus communis L.) cultivars and subsequently developed a subset of 1096 pear SNPs into high throughput markers ...
Sara Montanari +17 more
doaj +1 more source
Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays [PDF]
, 2007 High-throughput SNP genotyping platforms use automated genotype calling algorithms to assign genotypes. While these algorithms work efficiently for individual platforms, they are not compatible with other platforms, and have individual biases that result
Edward M. Smith +15 more
core +2 more sources
Microarrays, 2016 The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands
openaire +2 more sources
SNPs Array Karyotyping in Non-Hodgkin Lymphoma [PDF]
Microarrays, 2015 The traditional methods for detection of chromosomal aberrations, which included cytogenetic or gene candidate solutions, suffered from low sensitivity or the need for previous knowledge of the target regions of the genome. With the advent of single nucleotide polymorphism (SNP) arrays, genome screening at global level in order to find chromosomal ...
Etebari, Maryam +2 more
openaire +3 more sources
A multi-array multi-SNP genotyping algorithm for Affymetrix SNP microarrays [PDF]
Bioinformatics, 2007 AbstractMotivation: Modern strategies for mapping disease loci require efficient genotyping of a large number of known polymorphic sites in the genome. The sensitive and high-throughput nature of hybridization-based DNA microarray technology provides an ideal platform for such an application by interrogating up to hundreds of thousands of single ...
Xiao, Yuanyuan +3 more
openaire +4 more sources
Genetic analysis of products of conception using a HLPA/SNP-array strategy
Molecular Cytogenetics, 2019 Background Fetal chromosomal abnormalities was the most frequent cause of miscarriage, and the traditional testing method G-banded karyotyping has limitations.
Jun Mao +6 more
doaj +1 more source
The advantages of SNP arrays over CGH arrays [PDF]
Molecular Cytogenetics, 2014 In recent years, with the rapid development of Chromosomal Micro-array Analysis (CMA), the resolution limit of 5Mb which was imposed by conventional cytogenetics, has been significantly lowered. Currently, array CGH is the most widely used CMA technology.
openaire +3 more sources