Results 111 to 120 of about 10,843 (260)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Social media research: influencing the influencers

open access: yes, 2012
One of the central concepts in marketing theory is the idea that some individuals are more\ud influential than others, and that these influencers play a central role in driving adoption of\ud new products and services. From a customer service perspective, when these influencers\ud are dissatisfied, they are able to drive disproportionally large numbers
Nunan, Dan, Cook, Alessia
openaire  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The Role of Social Media Influencers and Online Reviews in Shaping Purchase Intention of Halal Cosmetics: A Study on Cusumers in Indonesia

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
Halal cosmetic products are increasingly popular among global consumers, especially in Indonesia, one of Asia's fastest-growing cosmetic markets. Social media marketing is the primary strategy for promoting halal cosmetic products through influencers as
Syariifah Saniyyah Al Gadri   +2 more
doaj  

Social media influencer marketing

open access: yes, 2017
The aim of this master thesis was to explore the effects of sponsorships on the perceived source credibility of social media influencers in the fitness industry. In order to answer the research question how sponsorships affect the perceived source credibility, a qualitative approach in the form of focus group interviews and a quantitative approach in ...
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

A model of purchase intention of complementary and alternative medicines: the role of social media influencers' endorsements. [PDF]

open access: yesBMC Complement Med Ther, 2023
Gülpınar G   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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