Results 51 to 60 of about 2,992 (185)
The use of medications approved for alcohol use disorders in Italy
BackgroundItaly has the highest per capita alcohol consumption among European countries. Several pharmacological treatments for alcohol use disorders (AUDs) are currently available in Italy, but no consumption data are available.
Filomena Fortinguerra +2 more
doaj +1 more source
Clinical and polysomnographic course of childhood narcolepsy with cataplexy. [PDF]
Our aim was to investigate the natural evolution of cataplexy and polysomnographic features in untreated children with narcolepsy with cataplexy. To this end, clinical, polysomnographic, and cataplexy-video assessments were performed at diagnosis (mean ...
American Academy of Sleep Medicine +58 more
core +2 more sources
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand +19 more
wiley +1 more source
Pain-related diseases and sleep disorders [PDF]
Pain and sleep share mutual relations under the influence of cognitive and neuroendocrine changes. Sleep is an important homeostatic feature and, when impaired, contributes to the development or worsening of pain-related diseases.
Roizenblatt, Marina +3 more
core +4 more sources
Implication of the thalamus in sleep alterations observed in Alzheimer's disease
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep‐dependent memory ...
Carla Burnet‐Merlin +2 more
wiley +1 more source
Sodium Oxybate: A Cause of Extreme Involuntary Weight Loss in a Young Lady
We present a case of a young lady with extreme involuntary weight loss and alarming constitutional symptoms found ultimately to be all due to a single medication’s side effects.
Michael G. Noujaim +2 more
doaj +1 more source
Gamma-hydroxybutyric acid (GHB) is a potent, short-acting central nervous system depressant as well as an inhibitory neurotransmitter or neuromodulator derived from gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter.
Suryun Jung +3 more
doaj +1 more source
Abstract Background and aims Gamma‐hydroxybutyrate (GHB) is an endogenous neurochemical and illicit synthetic drug. Its precursors, gamma‐butyrolactone (GBL) and 1,4‐butanediol (1,4‐BD), are often used as substitutes. We aimed to describe GHB‐related harms in New South Wales (NSW), Australia.
Krista J. Siefried +9 more
wiley +1 more source
Psychosis in patients with narcolepsy as an adverse effect of sodium oxybate
Aim: Hypnagogic and hypnopompic hallucinations are characteristic symptoms of narcolepsy, as are excessive daytime sleepiness, cataplexy and sleep paralysis.
Tomi eSarkanen +7 more
doaj +1 more source
Case Report: Burden of Illness in Narcolepsy Type 1: Hikikomori in a Teenage Girl
Narcolepsy type 1 (NT1) deeply impacts on quality of life, especially during adolescence, with NT1 children and adolescents that frequently report difficulties in integration with peers and decreased participation in after-school activities.
Marco Filardi +12 more
doaj +1 more source

