Stability analysis of sodium saccharin in fried nuts and seeds—Determination of sodium saccharin and o-sulfamoylbenzoic acid by HPLC [PDF]
Since the invention of synthetic sweeteners, there has been considerable debate regarding the safety of some of these sweeteners due to their poor thermal stability.
Li Mu +7 more
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Safety of a feed additive consisting of sodium saccharin for suckling and weaned piglets, fattening pigs, calves for rearing and for fattening (FEFANA asbl) [PDF]
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of sodium saccharin as a sensory feed additive (flavouring compound) for suckling and weaned piglets, fattening pigs, calves for rearing and ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +25 more
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Drinking Non-nutritive Sweetness Solution of Sodium Saccharin or Rebaudioside a for Guinea Pigs: Influence on Histologic Change and Expression of Sweet Taste Receptors in Testis and Epididymis [PDF]
Saccharin sodium and rebaudioside A are extensively used as non-nutritive sweeteners (NNSs) in daily life. NNSs elicit a multitude of endocrine influences on animals, differing across species and chemically distinct sweeteners, whose exposure induce ...
Ting Shen, Junrong Li, Junrong Li
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Exposure of HepaRG Cells to Sodium Saccharin Underpins the Importance of Including Non-Hepatotoxic Compounds When Investigating Toxicological Modes of Action Using Metabolomics [PDF]
Metabolites represent the most downstream information of the cellular organisation. Hence, metabolomics experiments are extremely valuable to unravel the endogenous pathways involved in a toxicological mode of action. However, every external stimulus can
Matthias Cuykx +5 more
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Safety and efficacy of sodium saccharin when used as a feed flavour for piglets, pigs for fattening, calves for rearing and calves for fattening [PDF]
Sodium saccharin is intended to be used as a sweetener in feed and water for drinking for piglets, pigs for fattening and veal calves. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) considers the proposed maximum use level
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
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The study of the relationship between food additives and the childhood asthma based on metabolome analysis [PDF]
BackgroundEpidemiological evidence suggests health risks arise from intake of food additives. This study aims to investigate the mechanisms linking food additives to childhood asthma through a metabolomics strategy.MethodsA total of 120 children with ...
Mingcong Chen +7 more
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Re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives [PDF]
This opinion deals with the re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives. Saccharin is the chemically manufactured compound 1,2‐benzisothiazol‐3(2H)‐one‐1,1‐dioxide.
EFSA Panel on Food Additives and Flavourings (FAF) +42 more
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Determination of saccharin in pharmaceuticals by high performance thin layer chromatography [PDF]
A simple, accurate and selective high performance thin layer chromatographic method for the determination of saccharin in pharmaceuticals has been developed.
Čakar Mira, Popović Gordana
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In order to get the information regarding the sweetener-water and sweetener-sweetener interactions, densities of sodium saccharin in water and (0.1, 0.3, and 0.5) m fructose have been measured at (298.15, 303.15, 308.15, and 313.15) K by the use of ...
Sanjeevan J. Kharat, Sachin M. Munde
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Sodium saccharin and sodium saccharin + sodium bicarbonate consumptions in rats: A comparison [PDF]
Seventy-three thirsty, hungry, or hungry and thirsty rats were given a choice between water and sodium saccharin in concentrations which were equivalent to the sodium saccharin component of a compound used in earlier studies (Strouthes & Navarick, 1967; Strouthes, Volo, & Unger, 1974) and which consisted of sodium saccharin and soda bicarbonate mixed ...
Andrew Strouthes, Alfred Volo
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