Results 11 to 20 of about 4,987 (175)

Saccharin Aggravates Eosinophilic Esophagitis via MAPK3 Interaction: A Network Toxicology and Machine Learning Study With SPR Analysis. [PDF]

Food Sci Nutr
This study provides a novel molecular perspective on the role of dietary factors in EoE pathogenesis. We establish saccharin as a key aggravating factor for EoE and highlight MAPK3 as a compelling therapeutic target. Our findings suggest that controlling saccharin intake represents a direct and beneficial dietary management strategy for EoE.
Yang Y, Guo T, Li P, Gao K, Ning X, Zhou L, Zhou W, Zeng B.   +7 more
europepmc   +2 more sources

Effects of Adding Ferula badrakema Root Powder with and Without Sodium Saccharin Sweetener to the Diet on Growth Performance, Immune System and Blood Metabolites of Broiler Chickens [PDF]

پژوهشهای علوم دامی ایران, 2023
Introduction:  The Ferula badrakema from the Apiaceae family is a resinous plant with a strong smell that is native to Iran (Rechinger et al., 1994). The anti-bacterial and anti-fungal properties of Ferula badrakema are believed to be due to its high ...
Hamidreza Khajavi, Ahmad Hassanabadi, Mahdi Askari   +2 more
doaj   +1 more source

Reducing sulfur to improve thermal embrittlement in electrodeposited nickel using citric acid

Results in Surfaces and Interfaces, 2020
Electrodeposited nickel usage has been limited owing to thermal embrittlement at high temperatures. Electrodeposited nickel generally contains sulfur, and the grain boundary segregation of sulfur leads to thermal embrittlement.
Atsuya Watanabe, Yorinobu Takigawa
doaj   +1 more source

D2 Receptors and Sodium Ion Channel Blockades of the Basolateral Amygdala Attenuate Lithium Chloride-Induced Conditioned Taste Aversion Applying to Cancer Chemotherapy Nausea and Vomiting

Brain Sciences, 2023
Cancer patients regularly suffer from the behavioral symptoms of chemotherapy-induced nausea and vomiting. Particularly, it is involved in Pavlovian conditioning. Lithium chloride (LiCl) was used as the unconditioned stimulus (US) and contingent with the
Zhi-Yue Gao, Chung Ming Huang, Cai-N Cheng, Andrew Chih-Wei Huang   +3 more
doaj   +1 more source

Copper(II) Prevents the Saccarine-Dialkylcyanamide Coupling by Forming Mononuclear (Saccharinate)(Dialkylcyanamide)copper(II) Complexes

Inorganics, 2021
The reaction in the system CuII/sacNa(H)/NCNR2 (sacNa(H) = sodium saccharinate (saccharin); R = Me, Et) results in the formation of the complexes [Cu(sac)2(NCNR2)(H2O)2] (R = Me 1, Et 2) instead of the expected products derived from the saccharin ...
Yulia N. Toikka, Dar’ya V. Spiridonova, Alexander S. Novikov, Nadezhda A. Bokach   +3 more
doaj   +1 more source

Drinking Water with Saccharin Sodium Alters the Microbiota-Gut-Hypothalamus Axis in Guinea Pig

Animals, 2021
The effects of saccharin, as a type of sweetener additive, on the metabolism and development of mammals are still controversial. Our previous research revealed that saccharin sodium (SS) promoted the feed intake and growth of guinea pigs.
Junrong Li, Shanli Zhu, Zengpeng Lv, Hongjian Dai, Zhe Wang, Quanwei Wei, Enayatullah Hamdard, Sheeraz Mustafa, Fangxiong Shi, Yan Fu   +9 more
doaj   +1 more source

Menthol-like cooling compounds, including (R)-(-)-carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K. [PDF]

FEBS Open Bio
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Saito M, Misaka T.
europepmc   +2 more sources

APLICAÇÃO DA ESPECTROSCOPIA NO INFRAVERMELHO E DIFRAÇÃO DE RAIO-X NA DETERMINAÇÃO DE SACARINA EM ADOÇANTES LÍQUIDOS ARTIFICIAIS PELO MÉTODO VOLUMÉTRICO COM AG+

Eclética Química, 2018
The use of sweeteners liquid from saccharin sodium is a public health issue by the relationship with obesity and a source of sodium. The  levels of saccharin were studied in four different manufacturers in samples from trade in Vitória / ES, between ...
Jhonatas de Souza Lima, Mauro Cesar Dias, Túlio Matencio   +2 more
doaj   +1 more source

Effect of sodium saccharin on the neonatal rat bladder. [PDF]

Scanning microscopy, 1995
In a two-generation bioassay, high doses of dietary sodium saccharin (NaSac) produce bladder carcinoma in rats, whereas acid saccharin (HSac) does not effect the urothelium. NaSac and HSac administered as 5% of the diet to F0 Sprague-Dawley (SD) and F344 rats, continued through to the weaned male rats for ten additional weeks.
Cohen, Samuel M., Cano, Martin, St. John, Margaret K., Garland, Emily M., Khachab, Mohamad, Ellwein, Leon B.   +5 more
openaire   +2 more sources

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn’s disease. The ENIGMA study

Gut Microbes, 2023
Food additives have been linked to the pro-inflammatory microbial dysbiosis associated with Crohn’s disease (CD) but the underlying ecological dynamics are unknown.
J.J. Jimenez Loayza, S. Kang, L. Schooth, J. J. Teh, A. de Klerk, E. K. Noon, J. Zhang, J. Hu, A. L. Hamilton, A. Wilson-O’Brien, G. L. Trakman, W. Lin, J. Ching, L. Or, J.J.Y. Sung, J. Yu, S.C. Ng, M.A. Kamm, M. Morrison   +18 more
doaj   +1 more source