Results 51 to 60 of about 216,158 (286)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Online Usage of Biomechanical and Simulation Software in Analysis of the Performances of Rehabilitation Robots, Using Simulation Technique

مجله پژوهش در علوم توانبخشی, 2020
Introduction: Rehabilitation robots have the ability to assist the patients with paralysis and semi-paralysis. Besides, these robots are capable of being programmed to perform various rehabilitation methods.
Maryam Khamar, Mehdi Edrisi, Saeed Forghany   +2 more
doaj   +1 more source

Socially-Assistive Robots to Support Learning in Students on the Autism Spectrum: Investigating Educator Perspectives and a Pilot Trial of a Mobile Platform to Remove Barriers to Implementation

Sensors, 2022
Technology offers educators tools that can tailor learning to students’ learning styles and interests. Research into the use of socially-assistive robots as a learning support for children on the autism spectrum are showing promising results. However, to
David Silvera-Tawil, Susan Bruck, Yi Xiao, DanaKai Bradford   +3 more
doaj   +1 more source

CHES robotic observation software kit

Frontiers in Astronomy and Space Sciences, 2022
CHES (changing event survey) is an optical survey program that not only aims at searching fast-moving RSOs in the sky for space domain awareness but also takes other scientific goals into account, such as NEO and transient events. After the success of the first array located at the Yaoan site in China, it evolved into a wider network consisting of ...
Chen Zhang, Chen Zhang, Can Zhu
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

OpenSYMORO: An open-source software package for Symbolic Modelling of Robots [PDF]

, 2014
International audienceThis paper presents OpenSYMORO, an open-source software package for symbolic modelling of robots. This software package is based on SYMORO+ software package.
Ecorchard, Gaël, Khalil, Wisama, Khomutenko, Bogdan, Lemoine, Philippe, Mukhanov, Izzatbek, Vijayalingam, Aravindkumar   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Building the executive system of autonomous aerial robots using the Aerostack open-source framework

International Journal of Advanced Robotic Systems, 2020
A variety of open-source software tools are currently available to help building autonomous mobile robots. These tools have proven their effectiveness in developing different types of robotic systems, but there are still needs related to safety and ...
Martin Molina, Abraham Carrera, Alberto Camporredondo, Hriday Bavle, Alejandro Rodriguez-Ramos, Pascual Campoy   +5 more
doaj   +1 more source

Simulation and Implementation of Obstacle Avoidance and Synchronization Tasks using Probabilistic and Timed Supervisory Control Theory in Swarm Robotics [PDF]

مجله مدل سازی در مهندسی, 2018
Due to difficulties in formal implementation of swarm robotic systems, controlling software of such systems is developed in an ad-hoc manner and with trial and error. So, it is hard to reuse these systems for other similar problems.
Faezeh Mirzaei, Ali Akbar Pouyan, Saeedeh Ferdosi   +2 more
doaj   +1 more source