Results 51 to 60 of about 315,815 (273)

Lanthanide-Mediated Dephosphorylation Used for Peptide Cleavage during Solid Phase Peptide Synthesis

open access: yesMolecules, 2013
Lanthanide(III) ions can accelerate the hydrolysis of phosphomonoesters and phosphodiesters in neutral aqueous solution. In this paper, lanthanide-mediated dephosphorylation has been applied in aqueous media as an orthogonal cleavage condition that can ...
Byunghee Yoo, Mark D. Pagel
doaj   +1 more source

Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines [PDF]

open access: yes, 2011
A versatile solid-phase approach to sequence-defined polyamidoamines was developed. Four different Fmoc-polyamino acid building blocks were synthesized by selective protection of symmetrical oligoethylenimine precursors followed by introduction of a ...
Badgujar, Naresh   +2 more
core   +1 more source

Peptide synthesis: ball-milling, in solution, or on solid support, what is the best strategy?

open access: yesBeilstein Journal of Organic Chemistry, 2017
While presenting particularly interesting advantages, peptide synthesis by ball-milling was never compared to the two traditional strategies, namely peptide syntheses in solution and on solid support (solid-phase peptide synthesis, SPPS).
Ophélie Maurin   +5 more
doaj   +1 more source

100th Anniversary of Macromolecular Science Viewpoint: Opportunities in the Physics of Sequence-Defined Polymers [PDF]

open access: yes, 2020
Polymer science has been driven by ever-increasing molecular complexity, as polymer synthesis expands an already-vast palette of chemical and architectural parameter space.
Perry, Sarah L., Sing, Charles E.
core   +3 more sources

A new method of N to C sequential ligation using thioacid capture ligation and native chemical ligation [PDF]

open access: yesRoyal Society Open Science, 2018
Sequential peptide ligation strategy becomes more and more important in large protein or long peptides chemical synthesis due to the limited peptide/protein size obtained by solid phase synthesis of individual peptides or even one-step peptide ligation ...
Wen Hou   +3 more
doaj   +1 more source

Peptides, solid-phase synthesis and characterization: Tailor-made methodologies

open access: yesElectronic Journal of Biotechnology, 2023
Background: Solid-Phase Peptide Synthesis (SPPS) is a mature technique widely used in research and in production. There are different approaches that fulfill the diverse requirements, regarding the number, quantity and quality of peptides.
Fanny Guzmán   +6 more
doaj   +1 more source

Synthesis, screening, and sequencing of cysteine-rich one-bead one-compound peptide libraries. [PDF]

open access: yes, 2008
Cysteine-rich peptides are valued as tags for biarsenical fluorophores and as environmentally important reagents for binding toxic heavy metals. Due to the inherent difficulties created by cysteine, the power of one-bead one-compound (OBOC) libraries has
Greaves, John   +3 more
core   +2 more sources

Synthesis of a Cyclooctapeptide, Cyclopurpuracin, and Evaluation of Its Antimicrobial Activity

open access: yesMolecules, 2023
Cyclopurpuracin is a cyclooctapeptide isolated from the methanol extract of Annona purpurea seeds with a sequence of cyclo-Gly-Phe-Ile-Gly-Ser-Pro-Val-Pro.
Rani Maharani   +9 more
doaj   +1 more source

On the selection and design of proteins and peptide derivatives for the production of photoluminescent, red-emitting gold quantum clusters [PDF]

open access: yes, 2013
Novel pathways of the synthesis of photoluminescent gold quantum clusters (AuQCs) using biomolecules as reactants provide biocompatible products for biological imaging techniques.
A Baksi   +48 more
core   +2 more sources

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