Results 41 to 50 of about 124,083 (150)

SASRIN™ a Versatile Tool in Peptide Synthesis and Solid-Phase Organic Chemistry

CHIMIA, 1999
The synthesis of the 4-(3-methoxy-4-(hydroxymethyl)phenoxymethyl) derivative of polystyrene-co-divinylbenzene (SASRIN™), its derivatives and its application in solid-phase peptide synthesis will be briefly reviewed in this paper.
Monika Mergler, Jacques Gosteli, Peter Grogg, Rolf Nyfeler, Rudolf Tanner   +4 more
doaj  

Reflections on a Copenhagen–Minneapolis Axis in Bioorganic Chemistry

Molecules
The international peptide community rejoiced when one of its most distinguished members, Morten Meldal of Denmark, shared the 2022 Nobel Prize in Chemistry. In fact, the regiospecific solid-phase “copper(I)-catalyzed 1,3-dipolar cycloaddition of terminal
George Barany, Paul R. Hansen
doaj   +1 more source

Automated Peptide Synthesizers and Glycoprotein Synthesis

Frontiers in Chemistry, 2022
The development and application of commercially available automated peptide synthesizers has played an essential role in almost all areas of peptide and protein research.
Jiekang Tian, Yaohao Li, Bo Ma, Zhongping Tan, Shiying Shang   +4 more
doaj   +1 more source

Insights into the preparation of selenopeptides awaiting functional validation for fatigue mitigation: a comprehensive review

Food Science of Animal Products
Fatigue, a debilitating condition arising from intense physical and mental stress, significantly impairs work capacity and well-being, yet effective molecular interventions remain scarce.
Yuxiao Guo, Wei Jia, Rong Zhang, Bo He, Fen Ao, Haizhen Mo   +5 more
doaj   +1 more source

Synthetic Peptide Purification via Solid-Phase Extraction with Gradient Elution: A Simple, Economical, Fast, and Efficient Methodology

Molecules, 2019
A methodology was implemented for purifying peptides in one chromatographic run via solid-phase extraction (SPE), reverse phase mode (RP), and gradient elution, obtaining high-purity products with good yields.
Diego Sebastián Insuasty Cepeda, Héctor Manuel Pineda Castañeda, Andrea Verónica Rodríguez Mayor, Javier Eduardo García Castañeda, Mauricio Maldonado Villamil, Ricardo Fierro Medina, Zuly Jenny Rivera Monroy   +6 more
doaj   +1 more source

SYNTHESIS OF OLIGOPEPTIDES OF DEFINED FRAGMENT COMPOSITION [PDF]

Journal of IMAB, 2011
The advantages of the solid-phase peptide synthesis were used. The peptide chain was built on specially processed insoluble polymer resin: Wang- and Rink Amide MBHA-resin.
Tamara Paypanova, Tatyana Hristova, Rumyana Cherkezova   +2 more
doaj  

Peptide Synthesis

Bio-Protocol, 2012
This protocol describes the synthesis of peptides for affinity testing and bioconjugate with solid phase peptide synthesizer at a small scale.
zheng miao, Zhen Cheng
doaj   +1 more source

Optimized Solid Phase-Assisted Synthesis of Dendrons Applicable as Scaffolds for Radiolabeled Bioactive Multivalent Compounds Intended for Molecular Imaging

Molecules, 2014
Dendritic structures, being highly homogeneous and symmetric, represent ideal scaffolds for the multimerization of bioactive molecules and thus enable the synthesis of compounds of high valency which are e.g., applicable in radiolabeled form as ...
Gabriel Fischer, Björn Wängler, Carmen Wängler   +2 more
doaj   +1 more source

Perfluorophenyl Derivatives as Unsymmetrical Linkers for Solid Phase Conjugation

Frontiers in Chemistry, 2018
Linkers play major roles in conjugation chemistry toward the advancement of drug discovery. Two different series of fluorinated linkers were introduced to the backbone of a model peptide using solid phase peptide synthesis. These fluorinated linkers have
Saba Alapour, Anamika Sharma, Anamika Sharma, Beatriz G. de la Torre, Deresh Ramjugernath, Neil A. Koorbanally, Fernando Albericio, Fernando Albericio   +7 more
doaj   +1 more source

Synthesis of N-peptide-6-amino-D-luciferin Conjugates

Frontiers in Chemistry, 2018
A general strategy for the synthesis of N-peptide-6-amino-D-luciferin conjugates has been developed. The applicability of the strategy was demonstrated with the preparation of a known substrate, N-Z-Asp-Glu-Val-Asp-6-amino-D-luciferin (N-Z-DEVD-aLuc).
Anita K. Kovács, Anita K. Kovács, Péter Hegyes, Gábor J. Szebeni, Gábor J. Szebeni, Lajos I. Nagy, László G. Puskás, László G. Puskás, Gábor K. Tóth   +8 more
doaj   +1 more source