Results 61 to 70 of about 132,649 (294)

Solid Phase Peptide Synthesis

, 2022
The research done last semester was on solid-phase peptide synthesis. The technique of solid-phase peptide synthesis consists of molecules that are bound to a solid frame and using protected amino acids, the peptide is synthesized step-by-step, obtaining
Martinez, Millie
core  

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]

, 2012
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A., Moreno Martínez, Virtudes, Carrion-Salip, Dolors, González-Cantó, A., Massaguer, A., Sadler, Peter, Llorens Duran, Rafael de, Massaguer i Vall-llovera, Anna, González Ibañez, Carlos, Massaguer, Anna, de Llorens, Rafael, Carrion-Salip, D, González, Carlos, Gómez-Pinto, Irene, Sadler, P. J., Moreno, Virtudes, Barragán, F., Barragán, Flavia, Sadler, P.J., Llorens, Rafael de, Marchán Sancho, Vicente, Sadler, Peter J., Carrion Salip, Dolors, Marchán, Vicente, González-Cantó, Alejandro   +24 more
core   +1 more source

IN4MER Biomaterial Ink: A Phosphorescent Biosensing Biomaterial Ink for Multiple Analytes (Glucose, Lactate, Oxygen) Measurements and Temperature Sensing Applications

Advanced Functional Materials, EarlyView.
Multianalyte, real‐time monitoring of bioprinted scaffolds remains challenging. Phosphorescence‐lifetime–based, optically responsive microparticles are embedded in diverse printable hydrogels (κ‐carrageenan, GelMA, PEGDA) to form biomaterial inks that report oxygen, glucose, lactate, and temperature.
Waqas Saleem, David Chimene, Berkley P. White, Kaivalya A. Deo, Jeremy L. Thomas, Nithin Chidambara, Cole Mandrona, Kirsten Landsgaard, Brian Ko, Roland Kaunas, Akhilesh K. Gaharwar, Michael J. McShane   +11 more
wiley   +1 more source

Automated Peptide Synthesizers and Glycoprotein Synthesis

Frontiers in Chemistry, 2022
The development and application of commercially available automated peptide synthesizers has played an essential role in almost all areas of peptide and protein research.
Jiekang Tian, Yaohao Li, Bo Ma, Zhongping Tan, Shiying Shang   +4 more
doaj   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Insights into the preparation of selenopeptides awaiting functional validation for fatigue mitigation: a comprehensive review

Food Science of Animal Products
Fatigue, a debilitating condition arising from intense physical and mental stress, significantly impairs work capacity and well-being, yet effective molecular interventions remain scarce.
Yuxiao Guo, Wei Jia, Rong Zhang, Bo He, Fen Ao, Haizhen Mo   +5 more
doaj   +1 more source

Synthetic Peptide Purification via Solid-Phase Extraction with Gradient Elution: A Simple, Economical, Fast, and Efficient Methodology

Molecules, 2019
A methodology was implemented for purifying peptides in one chromatographic run via solid-phase extraction (SPE), reverse phase mode (RP), and gradient elution, obtaining high-purity products with good yields.
Diego Sebastián Insuasty Cepeda, Héctor Manuel Pineda Castañeda, Andrea Verónica Rodríguez Mayor, Javier Eduardo García Castañeda, Mauricio Maldonado Villamil, Ricardo Fierro Medina, Zuly Jenny Rivera Monroy   +6 more
doaj   +1 more source

Solid-Phase Synthesis of Disulfide Heterodimers of Peptides [PDF]

Organic Letters, 2003
[structure: see text] The synthesis of the orthogonal disulfide template 1 and its use to synthesize unsymmetrical intermolecular disulfide bond peptides on a solid support are described. Application of template 1 to synthesize bioconjugates of cell permeable moieties based on the disulfide bond is demonstrated.
Amit K, Galande, Arno F, Spatola
openaire   +2 more sources

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation

Advanced Functional Materials, EarlyView.
We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali, Xinan Huang, Lucie Motyckova, Nicolas Moreno Gomez, Michal Skowicki, Cora‐Ann Schoenenberger, Peer Fischer, Cornelia G. Palivan   +7 more
wiley   +1 more source