Results 31 to 40 of about 1,029,734 (328)

An overview of recent progress in modern synthetic approach—combinatorial synthesis

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2020
Background In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small set up of reactions between different building blocks using solid-phase and solution-phase techniques ...
Chandravadivelu Gopi   +3 more
doaj   +1 more source

Solid-Phase Synthesis of ?-Oligopeptides

open access: yesCHIMIA, 1997
Fmoc-N-Protected ?-amino acids of (S)-configuration bearing the side chains of Ala, Val, Leu, and Phe in the 3- and 2-position have been prepared. Manual solid-phase synthesis (ortho-chlorotrityl-chloride resin) of the ?-heptapeptides H-?3-HVal-?
Gilles Guichard, Dieter Seebach
doaj   +2 more sources

Mechanochemical synthesis of AlCoCrFeNi powders via high-energy ball milling

open access: yesҚарағанды университетінің хабаршысы. Физика сериясы, 2023
AlCoCrFeNi powders in equimolar ratios were synthesized by mechanochemical synthesis on a high-energy ball milling machine (HEBM). The elemental and phase composition of AlCoCrFeNi powders before and after mechanochemical synthesis were investigated by ...
Е.Е. Камбаров   +3 more
doaj   +1 more source

Advances in Fmoc solid‐phase peptide synthesis

open access: yesJournal of Peptide Science, 2016
Today, Fmoc SPPS is the method of choice for peptide synthesis. Very‐high‐quality Fmoc building blocks are available at low cost because of the economies of scale arising from current multiton production of therapeutic peptides by Fmoc SPPS.
R. Behrendt, P. White, J. Offer
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Novel Solution- and Solid-Phase Syntheses of Heterocyclic Systems

open access: yesCHIMIA, 2003
Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity.
Gaelle Cabon   +4 more
doaj   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Organic Synthesis on Solid Phase. (Supports, Linkers, Reactions)

open access: yesMolecules, 2001
n ...
Florencio Zaragoza Dörwald
doaj   +1 more source

Solid‐Phase Synthesis of Oligosaccharides

open access: yesChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Diederichsen, Ulf, Wagner, Thomas
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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