Results 31 to 40 of about 1,029,734 (328)
An overview of recent progress in modern synthetic approach—combinatorial synthesis
Background In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small set up of reactions between different building blocks using solid-phase and solution-phase techniques ...
Chandravadivelu Gopi+3 more
doaj +1 more source
Solid-Phase Synthesis of ?-Oligopeptides
Fmoc-N-Protected ?-amino acids of (S)-configuration bearing the side chains of Ala, Val, Leu, and Phe in the 3- and 2-position have been prepared. Manual solid-phase synthesis (ortho-chlorotrityl-chloride resin) of the ?-heptapeptides H-?3-HVal-?
Gilles Guichard, Dieter Seebach
doaj +2 more sources
Mechanochemical synthesis of AlCoCrFeNi powders via high-energy ball milling
AlCoCrFeNi powders in equimolar ratios were synthesized by mechanochemical synthesis on a high-energy ball milling machine (HEBM). The elemental and phase composition of AlCoCrFeNi powders before and after mechanochemical synthesis were investigated by ...
Е.Е. Камбаров+3 more
doaj +1 more source
Advances in Fmoc solid‐phase peptide synthesis
Today, Fmoc SPPS is the method of choice for peptide synthesis. Very‐high‐quality Fmoc building blocks are available at low cost because of the economies of scale arising from current multiton production of therapeutic peptides by Fmoc SPPS.
R. Behrendt, P. White, J. Offer
semanticscholar +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Novel Solution- and Solid-Phase Syntheses of Heterocyclic Systems
Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity.
Gaelle Cabon+4 more
doaj +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
Organic Synthesis on Solid Phase. (Supports, Linkers, Reactions)
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Florencio Zaragoza Dörwald
doaj +1 more source
Solid‐Phase Synthesis of Oligosaccharides
AbstractFor Abstract see ChemInform Abstract in Full Text.
Diederichsen, Ulf, Wagner, Thomas
openaire +4 more sources
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source