Results 11 to 20 of about 1,687,750 (295)

Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus®

Molecules, 2015
Solid dispersions are a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
Jinwen Liu, Meijuan Zou, Hongyu Piao, Yi Liu, Bo Tang, Ying Gao, Ning Ma, Gang Cheng   +7 more
doaj   +2 more sources

Current Trends on Solid Dispersions: Past, Present, and Future [PDF]

Advances in Pharmacological and Pharmaceutical Sciences, 2022
Solid dispersions have achieved significant interest as an effective means of enhancing the dissolution rate and thus the bioavailability of a range of weakly water-soluble drugs.
Ruba Malkawi, Walla I. Malkawi, Yahia Al-Mahmoud, Jawad Tawalbeh   +3 more
doaj   +2 more sources

APPLICATION OF SOLID DISPERSIONS WITH NON STEROIDAL ANTI INFLAMMATORY DRUGS IN PHARMACY [PDF]

Разработка и регистрация лекарственных средств, 2019
The article provides a brief overview of the use of solid dispersions of NSAIDs with polymeric carriers. Solid dispersions are entered in various dosage forms for different purposes.
I. I. Krasnuk (Junior), L. V. Ovsyannikova, O. I. Stepanova, A. V. Belyatskaya, I. I. Krasnuk, Yu. Ya. Kharitonov, V. V. Grikh, T. M. Kosheleva, L. A. Korol   +8 more
doaj   +1 more source

Glucosamine-paracetamol spray-dried solid dispersions with maximized intrinsic dissolution rate, bioavailability and decreased levels of in vivo toxic metabolites

Drug Design, Development and Therapy, 2018
Ahmed Mahmoud Abdelhaleem Ali,1,2 Ahmed Khames,1,2 Majed Mansour Alrobaian,1 Mohammad Hamaidi,3 Mohammed AS Abourehab4,5 1Department of Pharmaceutics, Faculty of Pharmacy, Taif University, Taif, Kingdom of Saudi Arabia; 2Department of Pharmaceutics ...
Ali AMA, Khames A, Alrobaian MM, Hamaidi M, Abourehab MAS   +4 more
doaj   +1 more source

Solid Dispersions for Drug Delivery

, 2022
Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions.

core   +2 more sources

Triboelectrification and dissolution property enhancements of solid dispersions [PDF]

, 2015
The use of solid dispersion techniques to modify physicochemical properties and improve solubility and dissolution rate may result in alteration to electrostatic properties of particles.
Conway, Barbara R, Hiba Al-Hamidi (16203491), Šupuk, Enes, Conway, Barbara R., Kofi Asare-Addo (4172488), Al-Hamidi, Hiba, Owusu-Ware, Samuel, Asare-Addo, Kofi, Samuel Owusu-Ware (16228529), Barbara R. Conway (4172491), Enes Šupuk (16228532), Nokhodchi, Ali, Ali Nokhodchi (4465915), Conway, Barbara R.; id_orcid   +13 more
core   +1 more source

From colloidal dispersions to colloidal pastesthrough solid–liquid separation processes [PDF]

, 2005
Solid–liquid separation is an operation that starts with a dispersion of solid particles in a liquid and removes some of the liquid from the particles, producing a concentrated solid paste and a clean liquid phase.
Persello, J, Botet, Robert, Madeline, J.B., Martin, C., Cabane, Bernard, Schweins, R., Cabane, B., Schweins, R, Persello, J., Botet, R., Meireles, Martine, Martin, Céline   +11 more
core   +1 more source

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones

Asian Journal of Pharmaceutical Sciences, 2017
Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai, Chunguang Li, George Binh Lenon, Charlie C.L. Xue, Weize Li   +4 more
doaj   +1 more source

The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000 [PDF]

Advanced Pharmaceutical Bulletin, 2015
Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion.
Jafar Akbari, Majd Saeedi, Katayoun Morteza-Semnani, Hamid Reza Kelidari, Farshad Sadegh Moghanlou, Gity Zareh, Sohrab Rostamkolaei   +6 more
doaj   +1 more source

Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development [PDF]

Advanced Pharmaceutical Bulletin, 2017
Purpose: A comparative study was carried out between surface solid dispersion (SSD) and solid dispersion (SD) of meloxicam (MLX) to assess the solubility and dissolution enhancement approach and thereafter develop as patient friendly orodispersible tablet.
Mayank Chaturvedi, Manish Kumar, Kamla Pathak, Shailendra Bhatt, Vipin Saini   +4 more
openaire   +3 more sources