Results 11 to 20 of about 26,284 (265)

The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000 [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion.
Jafar Akbari   +6 more
doaj   +1 more source

Enhancing Dissolution of Ibuprofen via Solid Dispersion Using Hydrophilic Carrier and Fast Dissolving Sugars

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
In this study, solid dispersion using hydrophilic carriers (polyethylene glycols) and fast dissolving sugars (sorbitol and lactose) has been employed to enhance dissolution and hence the bioavailability of ibuprofen.
Wedad Kamal Ali   +3 more
doaj   +1 more source

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai   +4 more
doaj   +1 more source

Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Purpose: A comparative study was carried out between surface solid dispersion (SSD) and solid dispersion (SD) of meloxicam (MLX) to assess the solubility and dissolution enhancement approach and thereafter develop as patient friendly orodispersible tablet.
Mayank Chaturvedi   +4 more
openaire   +3 more sources

BIOAVAILABILITY AND EROSIVE ACTIVITY OF SOME NON-STEROIDAL ANTI-INFLAMMATORY DRUGS SOLID-DISPERSIONS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1986
Solid dispersions of mefenamic acid, azapropazone, glafenine and floctafenine were prepared with PVP K25 and PEG 6000 in a ratio of 1:1 w/w. Bioavailability and erosive activity of these drugs were investigated using their solid dispersions. The obtained
A. Nouh, A. G. Abd El-Gawad, E. Ramadan
doaj   +1 more source

SOLUBILITY AND DISSOLUTION ENHANCEMENT OF KETOTIFEN BY SOLID DISPERSION TECHNIQUE [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2015
Ketotifen (KT) solid dispersions and physical mixtures were prepared with the objective of solubility and dissolution improvement using Hydroxypropyl-Beta-Cyclodextrin (HP-β-CD), Pluronic 127 (PF-127), Pluronic 68 (PF-68), Polyethylene glycol 6000 (PEG ...
Omnia Mahmoud   +2 more
doaj   +1 more source

Development and characterization of nifedipine-amino methacrylate copolymer solid dispersion powders with various adsorbents

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Solid dispersions of nifedipine (NDP), a poorly water-soluble drug, and amino methacrylate copolymer (AMCP) with aid of adsorbent, that is, fumed silica, talcum, calcium carbonate, titanium dioxide, and mesoporous silica from rice husks (SRH), were ...
Yotsanan Weerapol   +5 more
doaj   +1 more source

EFFECT OF SOLID DISPERSIONS ON THE SOLUBILITY OF METRONIDAZOLE

open access: yesФармация и фармакология (Пятигорск), 2021
The aim of the work is to study the effect of solid dispersions using polyethylene glycols of various molecular weights on the solubility of metronidazole in water. Metronidazole is an antimicrobial and antiprotozoal drug.
I. I. Krasnyuk (Jr.)   +8 more
doaj   +1 more source

Polyelectrolyte Complex Based Interfacial Drug Delivery System with Controlled Loading and Improved Release Performance for Bone Therapeutics

open access: yesNanomaterials, 2016
An improved interfacial drug delivery system (DDS) based on polyelectrolyte complex (PEC) coatings with controlled drug loading and improved release performance was elaborated.
David Vehlow   +5 more
doaj   +1 more source

Current Trends on Solid Dispersions: Past, Present, and Future

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2022
Solid dispersions have achieved significant interest as an effective means of enhancing the dissolution rate and thus the bioavailability of a range of weakly water-soluble drugs.
Ruba Malkawi   +3 more
doaj   +1 more source

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