Results 11 to 20 of about 130,260 (303)
Molecular Interactions in Solid Dispersions of Poorly Water-Soluble Drugs
Pharmaceutics, 2020 Physicochemical characterization is a crucial step for the successful development of solid dispersions, including the determination of drug crystallinity and molecular interactions.
Thao T. D. Tran, Phuong H. L. Tran
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Pharmaceutics, 2023 Loratadine (LRD), a non-sedating and slow-acting antihistamine, is often given in combination with short-onset chlorpheniramine maleate (CPM) to increase efficacy. However, LRD has poor water solubility resulting in low bioavailability.
Krit Suknuntha +3 more
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Journal of Clinical Rheumatology and Immunology, 2023 Background Ketoprofen (KPN) is commonly prescribed drug to alleviate pain related with rheumatoid arthritis (RA). However, KETO belongs to the BCS class-II category, characterized by poor water solubility, resulting in less dissolution capability leading
Pankajkumar Yadav
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Intermolecular interaction and solid state characterization of abietic acid/chitosan solid dispersions possessing antimicrobial and antioxidant properties [PDF]
, 2018 The aim of this work was to prepare and characterize solid dispersions of abietic acid (AB) and chitosan (CS) to investigate how formulation of the mixture may help in the battle against microbial colonization in different areas, such as the biomedical ...
Argent Richard, H. +6 more
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Asian Journal of Pharmaceutical Sciences, 2018 Dissolution molecular mechanism of solid dispersions still remains unclear despite thousands of reports about this technique. The aim of current research was to investigate the molecular dissolution mechanism of solid dispersions by molecular dynamics ...
TengIan Chan, Defang Ouyang
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British Journal of Pharmacy, 2023 The aim of this study was to design and evaluate the properties of solid dispersions of carbamazepine (CBZ) using poly (2-ethyl-2-oxazoline) (POX) as the hydrophilic carrier. These binary solid dispersions were prepared at varying drug loadings using the
Adebisi O Adeola
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The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000 [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion.
Jafar Akbari +6 more
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Asian Journal of Pharmaceutical Sciences, 2017 Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai +4 more
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From colloidal dispersions to colloidal pastesthrough solid–liquid separation processes [PDF]
, 2005 Solid–liquid separation is an operation that starts with a dispersion of solid particles in a liquid and removes some of the liquid from the particles, producing a concentrated solid paste and a clean liquid phase.
Botet, Robert +6 more
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Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014 In this study, solid dispersion using hydrophilic carriers (polyethylene glycols) and fast dissolving sugars (sorbitol and lactose) has been employed to enhance dissolution and hence the bioavailability of ibuprofen.
Wedad Kamal Ali +3 more
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