Results 21 to 30 of about 26,225 (262)
Molecular Interactions in Solid Dispersions of Poorly Water-Soluble Drugs
Pharmaceutics, 2020 Physicochemical characterization is a crucial step for the successful development of solid dispersions, including the determination of drug crystallinity and molecular interactions.
Thao T. D. Tran, Phuong H. L. Tran
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British Journal of Pharmacy, 2023 The aim of this study was to design and evaluate the properties of solid dispersions of carbamazepine (CBZ) using poly (2-ethyl-2-oxazoline) (POX) as the hydrophilic carrier. These binary solid dispersions were prepared at varying drug loadings using the
Adebisi O Adeola
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The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000 [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion.
Jafar Akbari +6 more
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Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014 In this study, solid dispersion using hydrophilic carriers (polyethylene glycols) and fast dissolving sugars (sorbitol and lactose) has been employed to enhance dissolution and hence the bioavailability of ibuprofen.
Wedad Kamal Ali +3 more
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Asian Journal of Pharmaceutical Sciences, 2017 Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai +4 more
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BIOAVAILABILITY AND EROSIVE ACTIVITY OF SOME NON-STEROIDAL ANTI-INFLAMMATORY DRUGS SOLID-DISPERSIONS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1986 Solid dispersions of mefenamic acid, azapropazone, glafenine and floctafenine were prepared with PVP K25 and PEG 6000 in a ratio of 1:1 w/w. Bioavailability and erosive activity of these drugs were investigated using their solid dispersions. The obtained
A. Nouh, A. G. Abd El-Gawad, E. Ramadan
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Journal for Research in Applied Sciences and Biotechnology, 2023 The majority of patients prefer to take their medications orally. However, many drugs' limited usage in oral administration is a result of their poor solubility. One important element that influences the rate of dissolution and bioavailability is solubility.
Sharanpreet Kaur +3 more
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SOLUBILITY AND DISSOLUTION ENHANCEMENT OF KETOTIFEN BY SOLID DISPERSION TECHNIQUE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2015 Ketotifen (KT) solid dispersions and physical mixtures were prepared with the objective of solubility and dissolution improvement using Hydroxypropyl-Beta-Cyclodextrin (HP-β-CD), Pluronic 127 (PF-127), Pluronic 68 (PF-68), Polyethylene glycol 6000 (PEG ...
Omnia Mahmoud +2 more
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Asian Journal of Pharmaceutical Sciences, 2017 Solid dispersions of nifedipine (NDP), a poorly water-soluble drug, and amino methacrylate copolymer (AMCP) with aid of adsorbent, that is, fumed silica, talcum, calcium carbonate, titanium dioxide, and mesoporous silica from rice husks (SRH), were ...
Yotsanan Weerapol +5 more
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EFFECT OF SOLID DISPERSIONS ON THE SOLUBILITY OF METRONIDAZOLE
Фармация и фармакология (Пятигорск), 2021 The aim of the work is to study the effect of solid dispersions using polyethylene glycols of various molecular weights on the solubility of metronidazole in water. Metronidazole is an antimicrobial and antiprotozoal drug.
I. I. Krasnyuk (Jr.) +8 more
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