Role of Phospholipids on Drug Dissolution in Polymer Solid Dispersions Prepared by Hot-Melt Extrusion. [PDF]
ACS Omegade Carvalho DM +7 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.This study explores the discrepancies between bulk mechanics and spatial mapping in a tissue‐mimetic hydrogel model. Microplastic particles create localized stiff mechanical microenvironments that are detectable by cellular‐scale nanoindentation but leave bulk properties unchanged as measured by rheology.
Ahron T. Verschleisser +3 more
wiley +1 more source
Engineering ofloxacin bioavailability through spray-dried HPMC and xanthan gum-based solid dispersions: enhanced solubility and therapeutic efficacy. [PDF]
RSC AdvPervez Lali S +9 more
europepmc +1 more source
Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy
Advanced Engineering Materials, EarlyView.Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang +6 more
wiley +1 more source
Continuous Processing Strategies for Amorphous Solid Dispersions of Itraconazole: Impact of Polymer Selection and Manufacturing Techniques. [PDF]
PharmaceuticsKshirsagar MM +4 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.Binder‐free laser powder bed fusion of 8YSZ with a femtosecond laser is used to map process windows linking scan strategy, heat accumulation, and grain growth. Time‐resolved thermography and simulations reveal thermal regimes that enable continuous, vitrified, and fine‐grained 8YSZ surface layers without absorptive additives and demonstrate ...
Markus Kühn +5 more
wiley +1 more source
The More the Better?─Vitamin E TPGS as a Release Enhancer for Ritonavir/PVPVA Amorphous Solid Dispersions. [PDF]
Mol PharmFahrig I +5 more
europepmc +1 more source
Advanced Engineering Materials, EarlyView.CT‐based finite element simulations combined with in situ X‐ray computed tomography are used to analyze insert pull‐out in nickel‐coated polymer foams. Despite variations in material parameters, deformation consistently concentrates within a narrow annular region around the insert.
Yannik Bautz +4 more
wiley +1 more source
Enhancing the Solubility and Dissolution of Apigenin: Solid Dispersions Approach. [PDF]
Int J Mol SciRosiak N +4 more
europepmc +1 more source
Design of a Multistable Finger Prosthesis with Programmable Metamaterials
Advanced Engineering Materials, EarlyView.This research article shows the development of a multistable programmble metamaterial for the use as a finger prosthesis. The material was designed on different hierarchical levels where the influence of geometrical parameters and combination of mechanical elements was explored.
Franziska Wenz +5 more
wiley +1 more source