Results 241 to 250 of about 414,318 (301)

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong   +5 more
wiley   +1 more source

Enantioselective Synthesis on the Solid Phase

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Leßmann, T., Waldmann, H.
openaire   +3 more sources

Solid phase synthesis of oligosaccharides

Tetrahedron Letters, 1996
Abstract An efficient and stereocontrolled solid-phase chemical synthesis of oligosaccarides using a new type of insoluble support (a copolymer of polyethylene glycol and polystyrene) is described. Several Lewis acids were tested as activators of the trichloroacetimidate 12 , used as glycosyl donor, in the dimer 13 formation.
ADINOLFI M   +4 more
openaire   +3 more sources

Solid phase synthesis of praziquantel

Tetrahedron Letters, 2006
The first solid phase synthesis of the important anthelmintic praziquantel is described. The synthesis is rapid and efficient. The method may be extended to the synthesis of libraries of urgently needed replacements for this drug.
M. Todd, S. El-Fayyoumy, W. Mansour
openaire   +1 more source

Solid Phase Synthesis of Oligosaccharides

2010
Oligosaccharides are involved in many fundamental biological processes. However, relatively little is known about the precise molecular mechanism of action of these macromolecules, because the complexity of these structures impeded their synthesis by chemical methods analogous to those employed to create oligonucleotides and peptides.
Weishaupt, M., Eller, S., Seeberger, P.
openaire   +3 more sources

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