Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
THF peroxide as a factor in generating desulphurised products from the solid-phase synthesis of phosphorothioate-modified oligonucleotides. [PDF]
Ren Q, Osawa T, Tatsuno M, Obika S.
europepmc +1 more source
Synthesis of Protected Thiophospho Amino Acids for Solid Phase Peptide Synthesis
Esteban Pomo-Villar +6 more
openalex +1 more source
Unravelling charge transport mechanisms in graphene nanosheet networks: by combining temperature‐dependent conductivity measurements with a Random Resistor Network model, this study identifies a transition from hopping‐dominated conduction to a band‐like transport mechanism.
Alessandro Grillo +9 more
wiley +1 more source
A solid phase traceless synthesis of quinoxalinones
Viktor Krchňák +2 more
openalex +1 more source
HKUST‐1/TiO2 composite materials show a very high photocatalytic hydrogen evolution rate which increases as a function of the irradiation time until reaching a plateau and even surpasses the performance of the 1%Pt/TiO2 material after three photocatalytic cycles.
Alisha Khan +9 more
wiley +1 more source
An efficient alternative to DBU in the oxathiaphospholane (OTP) method for the solid phase synthesis of P-stereodefined phosphorothioate analogs. [PDF]
Jastrzębska K.
europepmc +1 more source
Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić +9 more
wiley +1 more source
Solid-Phase Synthesis as a Tool to Create Exactly Defined, Branched Polymer Vectors for Cell Membrane Targeting. [PDF]
Elter JK +7 more
europepmc +1 more source
Solid‐Phase Synthesis and Combinatorial Technologies
Pierfausto Seneci
openalex +1 more source

