Results 21 to 30 of about 1,128,663 (346)
Solution-phase synthesis of pyrrole-imidazole polyamides [PDF]
, 2009 Pyrrole−imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on
Chenoweth, David M. +2 more
core +3 more sources
Use of continuous solid-phase synthesis to obtain phosphors based on strontium aluminate [PDF]
, 2016 The effect of conditions of continuous solid-phase synthesis on particle size distribution of nanostructured powders of strontium aluminate was studied.
Falkovich, Yulia Valerievna +3 more
core +1 more source
Solid-Phase Synthesis of Megamolecules
Journal of the American Chemical Society, 2020 This paper presents a solid-phase strategy to efficiently assemble multiprotein scaffolds-known as megamolecules-without the need for protecting groups and with precisely defined nanoscale architectures. The megamolecules are assembled through sequential reactions of linkers that present irreversible inhibitors for enzymes and fusion proteins ...
Blaise R. Kimmel +4 more
openaire +4 more sources
HOBt·DCHA-Mediated Synthesis of Sterically Hindered Peptides employing Fmoc-Amino Acid Chlorides in Both Solution-Phase and Solid Phase Methods [PDF]
, 2008 The synthesis of peptides employing Fmoc-amino acid chlorides in presence of HOBt·DCHA salt in solution as well as by the solid-phase methods is described. The coupling was found to be complete in 30 min and free from racemization.
Krishna, G.C. +2 more
core +1 more source
Frontiers in Chemistry, 2020 Peptoids hold status as peptide-mimetics with versatile biological applications due to their proteolytic stability and structural diversity. Among those that have been studied in different biological systems, are peptoids with dominant balanced ...
Abdullah Lone +5 more
doaj +1 more source
High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]
, 2008 A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C. +3 more
core +1 more source
Total wash elimination for solid phase peptide synthesis
Nature Communications, 2023 We present a process for solid phase peptide synthesis (SPPS) that completely eliminates all solvent intensive washing steps during each amino acid addition cycle.
Jonathan M. Collins +6 more
doaj +1 more source
Carbides and Nitrides of Zirconium and Hafnium. [PDF]
, 2019 Among transition metal carbides and nitrides, zirconium, and hafnium compounds are the most stable and have the highest melting temperatures. Here we review published data on phases and phase equilibria in Hf-Zr-C-N-O system, from experiment and ab ...
Hong, Qi-Jun +3 more
core +1 more source
Rhodiasolv PolarClean – a greener alternative in solid-phase peptide synthesis
Green Chemistry Letters and Reviews, 2021 PolarClean, a green solvent prepared through the valorization of a byproduct of Nylon-66 manufacturing, shows an excellent capacity to dissolve all Fmoc-amino acids and key coupling reagents and additives.
Ashish Kumar +3 more
doaj +1 more source
Molecules, 2011 The solid-phase synthesis of the first example of a new diphosphate AICAR derivative is reported. The new substance is characterized by the presence of a 5'-phosphate group while a second phosphate moiety is installed on a 5-hydroxypentyl chain attached ...
Gennaro Piccialli +7 more
doaj +1 more source