Results 21 to 30 of about 1,859,179 (392)
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Molecules, 2013 Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
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Solution-phase synthesis of pyrrole-imidazole polyamides [PDF]
, 2009 Pyrrole−imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on
Chenoweth, David M. +2 more
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High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]
, 2008 A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C. +3 more
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Carbides and Nitrides of Zirconium and Hafnium. [PDF]
, 2019 Among transition metal carbides and nitrides, zirconium, and hafnium compounds are the most stable and have the highest melting temperatures. Here we review published data on phases and phase equilibria in Hf-Zr-C-N-O system, from experiment and ab ...
Hong, Qi-Jun +3 more
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Frontiers in Chemistry, 2020 Peptoids hold status as peptide-mimetics with versatile biological applications due to their proteolytic stability and structural diversity. Among those that have been studied in different biological systems, are peptoids with dominant balanced ...
Abdullah Lone +5 more
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Total wash elimination for solid phase peptide synthesis
Nature Communications, 2023 We present a process for solid phase peptide synthesis (SPPS) that completely eliminates all solvent intensive washing steps during each amino acid addition cycle.
Jonathan M. Collins +6 more
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Use of continuous solid-phase synthesis to obtain phosphors based on strontium aluminate [PDF]
, 2016 The effect of conditions of continuous solid-phase synthesis on particle size distribution of nanostructured powders of strontium aluminate was studied.
Falkovich, Yulia Valerievna +3 more
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Rhodiasolv PolarClean – a greener alternative in solid-phase peptide synthesis
Green Chemistry Letters and Reviews, 2021 PolarClean, a green solvent prepared through the valorization of a byproduct of Nylon-66 manufacturing, shows an excellent capacity to dissolve all Fmoc-amino acids and key coupling reagents and additives.
Ashish Kumar +3 more
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HOBt·DCHA-Mediated Synthesis of Sterically Hindered Peptides employing Fmoc-Amino Acid Chlorides in Both Solution-Phase and Solid Phase Methods [PDF]
, 2008 The synthesis of peptides employing Fmoc-amino acid chlorides in presence of HOBt·DCHA salt in solution as well as by the solid-phase methods is described. The coupling was found to be complete in 30 min and free from racemization.
Krishna, G.C. +2 more
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ACS Sustainable Chemistry and Engineering, 2019 To replace dimethylformamide (DMF) in fluorenylmethoxycarbonyl (Fmoc) solid-phase peptide synthesis, we explored the application of mixtures of green solvents (green solvents mixtures for solid-phase peptide synthesis (GM-SPPS)) as combinations of Cyrene
L. Ferrazzano +6 more
semanticscholar +1 more source