Results 31 to 40 of about 1,067,178 (339)

Development of phospholipon®90H complex nanocarrier with enhanced oral bioavailability and anti-inflammatory potential of genistein

open access: yesDrug Delivery, 2023
Genistein (GEN), an isoflavonoid, offers multifunctional biological activities. However, its poor oral bioavailability, aqueous solubility, extensive metabolism, and short half-life restricted its clinical use.
Vaishnavi S. Shete   +4 more
doaj   +1 more source

Inclusion Complexes of a New Family of Non-Ionic Amphiphilic Dendrocalix[4]arene and Poorly Water-Soluble Drugs Naproxen and Ibuprofen

open access: yesMolecules, 2017
The inclusion complexes of a new family of nonionic amphiphilic calix[4]arenes with the anti-inflammatory hydrophobic drugs naproxen (NAP) and ibuprofen (IBP) were investigated. The effects of the alkyl chain’s length and the inner core of calix[4]arenes
Khalid Khan   +4 more
doaj   +1 more source

Effects of Sulfur Sources on Ruminal S Bioavailability, Fermentation Activity and Microbial Populations Measured In Vitro

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2023
The aim of this study was to better understand the ruminal solubility, bioavailability, effect on fermentation and microbiota of different sulfur (S) forms. In vitro fermentations with rumen fluid were conducted for 70hrs. Hay was incubated solely (CON),
Antal VIGH   +4 more
doaj   +1 more source

The determination of solubility parameters of solvents and polymers by means of correlations with other physical quantities [PDF]

open access: yes, 1975
Correlations of solvent solubility parameters with molar attraction constants and with properties like surface tension, dipole moment, and index of refraction have been explored.
Koenhen, D.M., Smolders, C.A.
core   +3 more sources

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

open access: yes, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
A.A. Hernandez Santiago   +22 more
core   +1 more source

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Impact of earthworms on trace element solubility in contaminated mine soils amended with green waste compost [PDF]

open access: yes, 2011
The common practice of remediating metal contaminated mine soils with compost can reduce metal mobility and promote revegetation, but the effect of introduced or colonising earthworms on metal solubility is largely unknown. We amended soils from an As/Cu
Hodson, Mark E.   +2 more
core   +2 more sources

Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation

open access: yesPharmaceutics, 2019
Honokiol (HK), a well-tolerated natural product, has many multiple pharmacological activities. However, its poor water solubility and low bioavailability limit its clinical application and development.
Li Wang   +4 more
doaj   +1 more source

Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]

open access: yes, 2006
Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille   +3 more
core   +4 more sources

Experimental Data and Modelling of the Solubility of High-Carotenoid Paprika Extract in Supercritical Carbon Dioxide

open access: yesMolecules, 2019
The studies of solubility of the paprika extract with a high concentration of carotenoids in carbon dioxide under the pressure of 20−50 MPa and at temperatures of 313.15−333.15 K were carried out using the static method.
Dorota Kostrzewa   +2 more
doaj   +1 more source

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