Results 61 to 70 of about 534,042 (160)
Germinal Center Selection and Plasma Cell Differentiation
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Germinal centers (GCs) are specialized microenvironments in which B cells undergo affinity maturation through iterative cycles of somatic hypermutation, proliferation and selection, generating antibodies with improved antigen‐binding properties.
Adrien Sprumont, Oliver Bannard
wiley +1 more source
PLoS ONE, 2014 BackgroundMesenchymal stem cells have prominent immune modulatory properties, which may have clinical applications; however their major source, bone marrow, is of limited availability.
Fernando de Sá Silva +11 more
doaj +1 more source
Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts
Reviews in Aquaculture, Volume 18, Issue 4, September 2026.ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík +2 more
wiley +1 more source
PLoS ONE, 2013 Common variable immunodeficiency (CVID) is characterized by defective B cell function, impaired antibody production, and increased susceptibility to bacterial infections.
Dominic Paquin-Proulx +9 more
doaj +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.Neutrophils acquire extracellular fatty acids or adipocyte‐derived lipids and store them as triglycerides, polarizing into a lipid‐laden phenotype. Lipid‐laden neutrophils are found in the peripheral blood of HFD‐fed mice and patients with MASLD. These neutrophils release extracellular vesicles enriched with triglycerides and microRNAs that deliver ...
Sanjeeb Shrestha +10 more
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, 2007 Mature dendritic cells (DCs) are the most potent antigen-presenting cells within the human immune system. However, Herpes simplex virus type 1 (HSV-1) is able to interfere with DC biology and to establish latency in infected individuals.
Roger D. Everett +17 more
core +1 more source
The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
MedComm, Volume 7, Issue 7, July 2026.Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source
Cell Transplantation, 2014 Cells derived from the placenta have become the focus of extensive research concerning their ability to be used for regenerative medicine or cellular therapies.
Richard Banas M.S. +3 more
doaj +1 more source
Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.Ataxin‐1 has been recently implicated in B cell regulation in the context of multiple sclerosis pathology. In this study, we used a multiomics pipeline to profile the B cell transcriptome, epigenome, and proteome in response to encephalitogenic challenges.
Jonathan J. Carver +6 more
wiley +1 more source
Tolerogenic IDO1+CD83− Langerhans Cells in Sentinel Lymph Nodes of Patients with Melanoma
, 2022 Langerhans cells (LCs) are crucial regulators of anti-cancer immune responses. Cancer, however, can alter DCs functions leading to tolerance. The enzyme indoleamine 2,3-dioxygenase (IDO1) plays a crucial role in this process.
Gianni Gerlini +4 more
core +1 more source