Results 41 to 50 of about 534,042 (160)

Involvement of membrane CD83 / soluble CD83 in autoimmune pemphigus

, 2022
Le pemphigus est un groupe hétérogène de maladies bulleuses auto-immunes intra-épithéliales où les lymphocytes B produisent des auto-anticorps pathogènes directement responsables des lésions bulleuses et érosives, cutanées et muqueuses.
Bohelay, Gérôme
core  

Targeting CD83 for the treatment of graft-versus-host disease

, 2013
Graft-versus-host disease (GVHD) is a common and often fatal complication of bone marrow transplantation. Antigen-presenting cells from donor and recipient play a critical role in the initiation and maintenance of GVHD.
Wang, Xiongfei, Liu, Xiaosong, MING Q. WEI, XIAOSONG LIU, Wei, Ming Q, XIONGFEI WANG   +5 more
core   +1 more source

Soluble mediators

, 2015
Measurement of cytokines (IL-10, IL-12 p70, IFN-gamma, TGF-beta), soluble CD83 and Prostaglandin E2 (PGE2)
Johan Carlsson (826313)
core   +1 more source

Tilting the Balance: Therapeutic Prospects of CD83 as a Checkpoint Molecule Controlling Resolution of Inflammation [PDF]

, 2022
Chronic inflammatory diseases and transplant rejection represent major challenges for modern health care. Thus, identification of immune checkpoints that contribute to resolution of inflammation is key to developing novel therapeutic agents for those ...
Dmytro Royzman, Astrid Strack, Elisabeth Zinser, Marosan, Anita, Sadeghi Shermeh, Atefeh, Steinkasserer, Alexander, Zinser, Elisabeth, Peckert-Maier, Katrin, Strack, Astrid, Atefeh Sadeghi Shermeh, Pia Langguth, Royzman, Dmytro, Wild, Andreas B., Anita Marosan, Alexander Steinkasserer, Langguth, Pia, Katrin Peckert-Maier, Andreas B. Wild   +17 more
core   +1 more source

Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes [PDF]

The transmembrane protein CD83, expressed on APCs, B cells, and T cells, can be expressed as a soluble form generated by alternative splice variants and/or by shedding.
Nicolette CA, Grogan EW, Steinkasserer A, Horvatinovich JM, DeBenedette MA, Norris M, Lemos H, Mellor AL, Tcherepanova IY   +8 more
core   +3 more sources

NK cells are negatively regulated by sCD83 in experimental autoimmune uveitis

Scientific Reports, 2017
Natural killer (NK) cells represent a subset of lymphocytes that contribute to innate immunity and have been reported to play a role in autoimmune uveitis. However, the mechanisms regulating NK cellular function in this condition remain unclear.
Wei Lin, Xuejing Man, Peng Li, Nannan Song, Yingying Yue, Bingqing Li, Yuanbin Li, Yufei Sun, Qiang Fu   +8 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Direct contact of platelets and their released products exert different effects on human dendritic cell maturation

BMC Immunology, 2008
Background Dendritic cells (DCs) are antigen presenting cells capable of inducing innate and adaptive immune responses. According to the stimulus and their maturation state, DCs induce immunogenic or tolerogenic responses.
Delézay Olivier, Olivier Thomas, Chavarin Patricia, Palle Sabine, Cognasse Fabrice, Hamzeh-Cognasse Hind, Pozzetto Bruno, Garraud Olivier   +7 more
doaj   +1 more source

Oncolytic Virus‐Engineered Extracellular Vesicles Rewire Glioblastoma Immunity

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Immunotherapy with oncolytic Herpes simplex virus type 1 (oHSV‐1) shows promise for glioblastoma; however, clinical benefit remains uncommon due to tumour‐ and host‐mediated immunosuppression, which limits immune targeting of residual glioblastoma stem‐like cells (GSCs). To address this barrier, extracellular vesicles (EVs) harvested from oHSV‐
Klaudia Kiel, Arpita Balakrishnan, Aleksandra Cabaj, Luiza Stanaszek, Maciej Przybylski, Dawid Stępnik, Marta Małuszek, Christopher Jannotta, Chiara Zoe Linke, Joanna Suszyńska‐Zajczyk, Monika Knaur, Agnieszka Szczypiorowska, Szymon Hryhorowicz, Bianka Świderska, Katarzyna Piwocka, Alexander Lee Ling, E. Antonio Chiocca, Agnieszka Bronisz, Jakub Godlewski   +18 more
wiley   +1 more source