Results 231 to 240 of about 217,506 (260)
Some of the next articles are maybe not open access.
Rheumatology, 1995
A number of investigators have reported that there are detectably elevated levels of interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) in the synovial fluids of rheumatoid arthritis (RA) patients. However, the precise role of IL-6 and sIL-6R in the pathogenesis of RA remains unclear.
M, Mihara +3 more
openaire +2 more sources
A number of investigators have reported that there are detectably elevated levels of interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) in the synovial fluids of rheumatoid arthritis (RA) patients. However, the precise role of IL-6 and sIL-6R in the pathogenesis of RA remains unclear.
M, Mihara +3 more
openaire +2 more sources
Serum-Soluble IL-2 Receptor and IL-6 Levels in Patients with Melanoma
Oncology, 2009Elevated soluble IL-2 receptor (sIL-2R) and IL-6 serum concentrations have been reported as adverse prognostic factors in several types of cancer. In order to determine whether these factors are predictive of metastatic progression in melanoma, sIL-2R and IL-6 levels were measured in sera from 172 patients with melanoma and 60 in healthy controls. Mean
M D, Boyano +8 more
openaire +2 more sources
DNA Sequence, 1995
A polymerase chain reaction assay (Lust J.A. et al. (1992). Cytokine 4:96-100) was used to detect a mRNA coding for a soluble IL-6 receptor in human hepatoma cells. In addition to the expected amplification product, we found a sequence (SR4) which could be aligned to it with 78% identity. After cloning and sequencing a genomic 2.5-2.7 kB EcoRI fragment
Snyers, L +3 more
openaire +3 more sources
A polymerase chain reaction assay (Lust J.A. et al. (1992). Cytokine 4:96-100) was used to detect a mRNA coding for a soluble IL-6 receptor in human hepatoma cells. In addition to the expected amplification product, we found a sequence (SR4) which could be aligned to it with 78% identity. After cloning and sequencing a genomic 2.5-2.7 kB EcoRI fragment
Snyers, L +3 more
openaire +3 more sources
Soluble IL-6 Receptor in Vitreous Fluid of Patients with Proliferative Diabetic Retinopathy
Japanese Journal of Ophthalmology, 2007To identify the biological reaction of soluble interleukin-6 receptor (sIL-6R) in the vitreous of patients with proliferative diabetic retinopathy (PDR).The subjects were 45 patients (45 eyes) with vitreoretinal diseases. The patients were divided into three groups: the PDR group comprised 28 patients (28 eyes) with PDR; the pre-proliferative diabetic ...
Miwako, Kawashima +4 more
openaire +2 more sources
Purification and Characterization of Soluble Human IL-6 Receptor Expressed in CHO Cells
The Journal of Biochemistry, 1990An immunosorbent assay system to detect genetically engineered IL-6 receptor (IL-6R) was established, whereby soluble IL-6 receptor (sIL-6R) was detected in the culture medium when sIL-6R cDNA was transfected into COS1 cells. A stably transformed Chinese hamster ovary (CHO) cell line constitutively expressing sIL-6R has been established.
Kiyoshi Yasukawa +11 more
openaire +2 more sources
Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID‐19
Journal of the American Heart Association, 2022Shengyuan Luo +2 more
exaly
The soluble IL-6 receptors: serum levels and biological function.
Cellular and molecular biology (Noisy-le-Grand, France), 2002IL-6 exerts its biological activities through interaction with specific receptors expressed on the surface of target cells. IL-6 binds first to a low-affinity (10(-9) M) subunit, a 80 kDa glycoprotein also called gp80 or IL-6R alpha. The IL-6/IL-6R alpha complex recruits the signal-transducing b subunit, a 130 kDa glycoprotein called gp130.
openaire +1 more source
A Novel Human-Specific Soluble Vascular Endothelial Growth Factor Receptor 1
Circulation Research, 2008Ahuva Itin, S Yagel, Eli Keshet
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2016
Xiaohan Lu, Fei Wang, Chuanming Xu
exaly
Xiaohan Lu, Fei Wang, Chuanming Xu
exaly