Results 51 to 60 of about 202,290 (315)
Asian Pacific Journal of Reproduction, 2020 Objective: To assess the association between genetic variants of transferrin receptor 2 (TFR2) exon 4 and anemia status and to describe the expression levels of several cytokines, hepcidin, soluble transferrin receptor and erythropoietin.
Dono Indarto +7 more
doaj +1 more source
Blood cytokine levels in patients with alcohol dependence during early withdrawal treatment
Taiwanese Journal of Psychiatry, 2023 Objectives: Alcohol is known to modulate the immune system, which is associated with the pathophysiology of alcohol dependence (AD). Interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R), and tumor necrosis factor-alpha (TNF-α) are widely studied immune ...
Shu-Hao Hsu +5 more
doaj +1 more source
Soluble Human Interleukin‐6 Receptor [PDF]
European Journal of Biochemistry, 1995 The extracellular domain of the human interleukin‐6 (IL‐6) receptor, comprising 339 amino acids following the signal peptide, has been expressed in baculovirus‐infected insect cells (Sf158). When the soluble receptor secreted into the culture medium was purified by affinity chromatography, using IL‐6 immobilized on Sepharose, 6 mg soluble receptor was ...
Oliver Weiergräber +10 more
openaire +2 more sources
Advances in Rheumatology, 2019 Background Rheumatoid arthritis is a risk factor for early mortality due to cardiovascular disease. Interleukin-33 appears to protect against the development of atherosclerosis.
Maria Raquel Costa Pinto +6 more
doaj +1 more source
Cytokine soluble receptors in perinatal and early neonatal life
Mediators of Inflammation, 2003 Background: In contrast to cellular receptors, soluble receptors do not enhance the cellular activation because they do not have transmembranic and cytoplasmic parts, acting thereby as endogenous regulatory mechanisms against systemic functions of ...
Efthimia Protonotariou +5 more
doaj +1 more source
Soluble interleukin-6 receptor levels in pleural effusions
Respiratory Medicine, 1996 Generation of soluble cytokine receptors is a general phenomenon, and the roles of several such receptors have been investigated in clinical settings. Unlike other soluble cytokine receptors, soluble interleukin-6 receptor (sIL-6R) can act as an agonist and thus is implicated as an important modulator in the acute-phase reaction of prolonged ...
Yokoyama, A. +5 more
openaire +2 more sources
Haematologica, 2018 Patients with anaplastic lymphoma kinase-positive anaplastic large cell lymphoma often present with B-symptoms or hemophagocytosis and generate an anti-tumor immune response.
Fabian Knörr +6 more
doaj +1 more source
Journal of Biological Chemistry, 2018 Interleukin (IL-)6 is the major pro-inflammatory cytokine within the IL-6 family. IL-6 signals via glycoprotein 130 (gp130) and the membrane-bound or soluble IL-6 receptor (IL-6R), referred to as classic or trans-signaling, respectively.
Paul Baran +8 more
semanticscholar +1 more source
A complex of the soluble interleukin‐6 receptor and interleukin‐6 is internalized via the signal transducer gp130 [PDF]
FEBS Letters, 1996 In human body fluids a soluble form of the interleukin‐6 receptor (sIL‐6R) has been found which together with interleukin‐6 (IL‐6) acts agonistically on cells expressing the signal transducer gp130. The means by which the sIL‐6R is removed from the circulation is unknown.
Graeve, Lutz +5 more
openaire +3 more sources
Mediators of Inflammation, 2002 Background: It has recently been shown that soluble interleukin-6 receptor (sIL-6R) alone or complexed with interleukin (IL)-6, besides their regulatory role in a wide variety of both normal and abnormal biologic reactions mediated by IL-6, could be an ...
E. Jablonska
doaj +1 more source