Results 31 to 40 of about 134,028 (256)

Effect of soluble interleukin-6 receptor α and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-α expression and its production by peripheral blood mononuclear cells

Mediators of Inflammation, 2002
Background: It has recently been shown that soluble interleukin-6 receptor (sIL-6R) alone or complexed with interleukin (IL)-6, besides their regulatory role in a wide variety of both normal and abnormal biologic reactions mediated by IL-6, could be an ...
E. Jablonska
doaj   +1 more source

A complex of the soluble interleukin‐6 receptor and interleukin‐6 is internalized via the signal transducer gp130 [PDF]

FEBS Letters, 1996
In human body fluids a soluble form of the interleukin‐6 receptor (sIL‐6R) has been found which together with interleukin‐6 (IL‐6) acts agonistically on cells expressing the signal transducer gp130. The means by which the sIL‐6R is removed from the circulation is unknown.
Graeve, Lutz, Korolenko, Tatjana A., Hemmann, Ulrike, Weiergräber, Oliver, Dittrich, Elke, Heinrich, Peter   +5 more
openaire   +3 more sources

Increased Pro-inflammatory Cytokines (TNF-a and IL-6) and Anti-inflammatory Compounds (sTNFRp55 and sTNFRp75) in Brazilian Patients during Exanthematic Dengue Fever

Memorias do Instituto Oswaldo Cruz, 1999
Pro-inflammatory cytokines, tumor necrosis factor (TNF-a), interleukin-6 (IL-6) and interleukin-1b (IL-1b) as well as anti-inflammatory compounds, soluble TNF-Receptor p55 (sTNFRp55), sTNFRp75 and IL-1 receptor antagonist (sIL-1Ra), were investigated in ...
Luzia MO Pinto, Solange A Oliveira, Elzinandes LA Braga, Rita MR Nogueira, Claire F Kubelka   +4 more
doaj   +1 more source

Kappa Free Light Chains, Soluble Interleukin-2 Receptor, and Interleukin-6 Help Explore Patients Presenting With Brain White Matter Hyperintensities

Frontiers in Immunology, 2022
IntroductionMany patients are referred to multiple sclerosis (MS) tertiary centers to manage brain white matter hyperintensities (WMH). Multiple diagnoses can match in such situations, and we lack proper tools to diagnose complex cases.ObjectiveThis ...
Michael Levraut, Michael Levraut, Cassandre Landes, Lydiane Mondot, Lydiane Mondot, Lydiane Mondot, Mikael Cohen, Mikael Cohen, Saskia Bresch, Vesna Brglez, Vesna Brglez, Barbara Seitz-Polski, Barbara Seitz-Polski, Christine Lebrun-Frenay, Christine Lebrun-Frenay   +14 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Experience in using the assessment of the level of soluble interleukin-6 receptor in the process of rehabilitation of patients according to the program of aerobic training

Клинический разбор в общей медицине
Aim. Demonstration of the validity of assessing the level of soluble interleukin-6 receptor (s-IL-6R) in the process of recovery of patients according to the program of aerobic physical activity (APF) after the virus and bacterial pneumonia.
Andrey Yu. Tretyakov, Alexandra V. Zhabskaya, Alexandra V. Zhabskaya, Oleg V. Yermilov, Oleg V. Yermilov, Petr K. Alferov, Petr K. Alferov, Mikhail A. Tretyakov, Mikhail A. Tretyakov, Valeria V. Soloshenko, Valeria V. Soloshenko, Olga G. Deeva, Olga G. Deeva   +12 more
doaj   +1 more source

Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests

BMC Immunology, 2019
Background Cytokines, chemokines, adipocytokines, soluble cell receptors, and immune activation markers play an important role in immune responsiveness and can provide prognostic value since they reflect underlying conditions and disease states.
Najib Aziz, Roger Detels, Joshua J. Quint, David Gjertson, Timothy Ryner, Anthony W. Butch   +5 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source